Gene Symbol | PRR13 |
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Entrez Gene | 54458 |
Alt Symbol | TXR1 |
Species | Human |
Gene Type | protein-coding |
Description | proline rich 13 |
Other Description | proline-rich protein 13|taxane-resistance protein |
Swissprots | Q6PKF9 Q6FIG7 Q0V8U0 Q6NXQ6 Q6MZP8 Q9NZ81 |
Accessions | CAD34947 EAW96702 EAW96703 EAW96704 EAW96705 Q9NZ81 AF217517 AAF67628 AK074398 BC001464 BC004512 BC014257 AAH14257 BC016064 AAH16064 BC021019 BC062322 BC066943 AAH66943 BC071979 BK005847 DAA05782 BX640962 CAE45980 CN392914 CR533459 CAG38490 HQ448476 ADQ32956 JF432575 ADZ15792 NM_001005355 NM_001005354 NP_001005354 NM_018457 NP_060927 |
Function | Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis. {ECO:0000269|PubMed:16847352}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16847352}. |
TXR1 CRISPR/Cas9 KO Plasmid (h) - sc-416345 from Santa Cruz Biotechnology
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TXR1 HDR Plasmid (h) - sc-416345-HDR from Santa Cruz Biotechnology
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TXR1 Double Nickase Plasmid (h) - sc-416345-NIC from Santa Cruz Biotechnology
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TXR1 Double Nickase Plasmid (h2) - sc-416345-NIC-2 from Santa Cruz Biotechnology
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TXR1 CRISPR Activation Plasmid (h) - sc-416345-ACT from Santa Cruz Biotechnology
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TXR1 CRISPR Activation Plasmid (h2) - sc-416345-ACT-2 from Santa Cruz Biotechnology
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TXR1 Lentiviral Activation Particles (h) - sc-416345-LAC from Santa Cruz Biotechnology
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TXR1 Lentiviral Activation Particles (h2) - sc-416345-LAC-2 from Santa Cruz Biotechnology
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TXR1 siRNA (h) - sc-95688 from Santa Cruz Biotechnology
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TXR1 shRNA Plasmid (h) - sc-95688-SH from Santa Cruz Biotechnology
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TXR1 shRNA (h) Lentiviral Particles - sc-95688-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU111951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17489 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17489 from Sigma-Aldrich
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PRR13 siRNA (Human) - CRJ0067 from Cohesion Biosciences
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shRNA set against Human PRR13(NM_001005354.2) - SHR143732 from Creative biogene
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shRNA set against Human PRR13(NM_018457.3) - SHR143750 from Creative biogene
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PRR13 shRNA Plasmid (Human) - CHJ0067 from Cohesion Biosciences
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PRR13 miRNA 3'UTR clone - MiUTR1H-08323 from Creative biogene
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PRR13 miRNA 3'UTR clone - MiUTR1H-08324 from Creative biogene
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