| Gene Symbol |
ARX
|
| Entrez Gene |
170302
|
| Alt Symbol |
CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
aristaless related homeobox
|
| Other Description |
aristaless-related homeobox, X-linked|cancer/testis antigen 121|homeobox protein ARX
|
| Swissprots |
Q96QS3
|
| Accessions |
EAW99031 EAW99032 Q96QS3 AA484051 AY038071 AAK93901 BC169333 BC169334 BF196892 BQ100952 BQ269551 CA775911 NM_139058 NP_620689
|
| Function |
Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}.
|
| Tissue Specificity |
Expressed predominantly in fetal and adult brain and skeletal muscle. Expression is specific to the telencephalon and ventral thalamus. There is an absence of expression in the cerebellum throughout development and also in adult. {ECO:0000269|PubMed:11889467, ECO:0000269|PubMed:11971879, ECO:0000269|PubMed:12359145}.
|