Gene Symbol | CERS6 |
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Entrez Gene | 253782 |
Alt Symbol | CERS5, LASS6 |
Species | Human |
Gene Type | protein-coding |
Description | ceramide synthase 6 |
Other Description | LAG1 homolog, ceramide synthase 6|longevity assurance homolog 6 |
Swissprots | Q8N617 Q32M63 Q6ZMG9 |
Accessions | CAY55976 CCF77042 Q6ZMG9 AI521447 AK023042 AK024891 AK091391 AK123214 AK172775 BAD18757 AL080192 BC030800 AAH30800 BC109284 AAI09285 BC109285 AAI09286 BE745491 BG206657 BM968545 BX393696 U52135 XM_005246440 XP_005246497 NM_001256126 NP_001243055 NM_203463 NP_982288 |
Function | May be involved in sphingolipid synthesis or its regulation. {ECO:0000250}. |
Subcellular Location | Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Sphingolipid signaling pathway, Sphingolipid metabolism |
LASS6 CRISPR/Cas9 KO Plasmid (h) - sc-403901 from Santa Cruz Biotechnology
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LASS6 HDR Plasmid (h) - sc-403901-HDR from Santa Cruz Biotechnology
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LASS6 Double Nickase Plasmid (h) - sc-403901-NIC from Santa Cruz Biotechnology
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LASS6 Double Nickase Plasmid (h2) - sc-403901-NIC-2 from Santa Cruz Biotechnology
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LASS6 CRISPR Activation Plasmid (h) - sc-403901-ACT from Santa Cruz Biotechnology
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LASS6 CRISPR Activation Plasmid (h2) - sc-403901-ACT-2 from Santa Cruz Biotechnology
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LASS6 Lentiviral Activation Particles (h) - sc-403901-LAC from Santa Cruz Biotechnology
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LASS6 Lentiviral Activation Particles (h2) - sc-403901-LAC-2 from Santa Cruz Biotechnology
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LASS6 siRNA (h) - sc-62553 from Santa Cruz Biotechnology
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LASS6 shRNA Plasmid (h) - sc-62553-SH from Santa Cruz Biotechnology
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LASS6 shRNA (h) Lentiviral Particles - sc-62553-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU156551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11565 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11565 from Sigma-Aldrich
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CERS6 siRNA (Human) - CRJ6654 from Cohesion Biosciences
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LASS6 RNAi - H00253782-R01 from Novus Biologicals
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CERS6 - MBS8214872 from MyBioSource
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shRNA set against Human CERS6 (NM_203463.2) - SHH262133 from Creative biogene
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Human CERS6 siRNA - orb277155 from Biorbyt
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CERS6 shRNA Plasmid (Human) - CHJ6654 from Cohesion Biosciences
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