| Gene Symbol |
GSDMB
|
| Entrez Gene |
55876
|
| Alt Symbol |
GSDML, PP4052, PRO2521
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
gasdermin B
|
| Other Description |
gasdermin-B|gasdermin-like protein
|
| Swissprots |
Q7Z377 B4DKK7 Q8TAX9 Q9P163 Q8WY76 Q9NX71
|
| Accessions |
CAD35038 EAW60612 EAW60613 EAW60614 EAW60615 Q8TAX9 AF119884 AAF69638 AF258572 AAG23775 AK000409 BAA91146 AK025174 AK057588 AK296607 BAG59219 BC025682 AAH25682 BP366854 BX538068 CAD97998 BX647700 CA488357 CB136981 EU526753 ACB37349 EU526754 ACB37350 EU526755 ACB37351 EU526756 ACB37352 EU832489 ACE87661 EU832569 ACE86971 XM_011525001 XP_011523303 XM_011525002 XP_011523304 XM_011525003 XP_011523305 XM_011525004 XP_011523306 XM_011525005 XP_011523307 XM_011525006 XP_011523308 XM_011525007 XP_011523309 XM_011525008 XP_011523310 XM_011525009 XP_011523311 XM_011525010 XP_011523312 XM_011525011 XP_011523313 XM_011525012 XP_011523314 XM_011525013 XP_011523315 XM_011525014 XP_011523316 XM_011525015 XP_011523317 XM_011525016 XP_011523318 XM_011525017 XP_011523319 XM_011525018 XP_011523320 XM_011525019 XP_011523321 XM_011525020 XP_011523322 XM_011525021 XP_011523323 XR_934504 NM_001042471 NP_001035936 NM_001165958 NP_001159430 NM_001165959 NP_001159431 NM_018530 NP_061000
|
| Function |
May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells. {ECO:0000269|PubMed:15010812, ECO:0000269|PubMed:18038310}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:18038310}. Note=Vesicular localization in the apical region of gastric chief cells and colonic surface mucous cells, and the basal region of neuroendocrine cells.
|
| Tissue Specificity |
Expressed in gastric, liver and colon cell lines, carcinomas and non-lesional tissues. {ECO:0000269|PubMed:18038310}.
|