| Gene Symbol |
KIR2DL3
|
| Entrez Gene |
3804
|
| Alt Symbol |
CD158B2, CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIR2DS5, KIRCL23, NKAT, NKAT2, NKAT2A, NKAT2B, p58
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
|
| Other Description |
CD158 antigen-like family member B2|MHC class I NK cell receptor|NK-receptor|NKAT-2|killer Ig-like inhibitory receptor|killer cell immunoglobulin-like receptor 2DL3|killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5|killer inhibitory receptor cl 2-3|natural killer associated transcript 2|natural killer cell inhibitory receptor KIR2DL3|natural killer-associated transcript 2|p58 NK receptor CL-6|p58 natural killer cell receptor clone CL-6|p58.2 MHC class-I specific NK receptor|p58.2 MHC class-I-specific NK receptor
|
| Swissprots |
P43631 Q9UQ70 Q6H2G9 P78402 Q14944 Q14945 O43472 P43628 Q14955 Q9UM51
|
| Accessions |
AAD03160 ACI49719 ADN34697 ADN34698 ADN34699 ADN34700 ADN34701 ADN34702 P43628 AF022048 AAB95321 AF135556 AAD48764 AF135566 AAD48760 AF135567 AAD48761 AF285435 AAG34926 AY789057 AAX23102 BC032422 AAH32422 BC050730 AAH50730 BC110613 AAI10614 DQ890622 ABM92239 DQ893791 ABM84717 FN395076 CAZ15556 FN552550 CBF06602 L41268 AAA69869 L76662 AAB36590 L76663 AAB36591 U24074 AAC50333 U50546 AAB17730 U73395 AAC51147 U96190 AAB54120 NM_015868 NP_056952 NM_014511
|
| Function |
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Natural killer cell mediated cytotoxicity, Graft-versus-host disease, Antigen processing and presentation
|
