| Gene Symbol |
RNF152
|
| Entrez Gene |
220441
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ring finger protein 152
|
| Other Description |
E3 ubiquitin-protein ligase RNF152
|
| Swissprots |
B3KV99 Q8N8N0 Q52LA4
|
| Accessions |
EAW63114 EAW63115 Q8N8N0 AK096495 BAC04805 AK122758 BAG53711 BC071787 BC094004 AAH94004 BC111956 AAI11957 XM_005266650 XP_005266707 XM_005266651 XP_005266708 XM_005266652 XP_005266709 XM_011525877 XP_011524179 XM_011525878 XP_011524180 XM_011525879 XP_011524181 XM_011525880 XP_011524182 NM_173557 NP_775828
|
| Function |
E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed. {ECO:0000269|PubMed:21203937}.
|
| Subcellular Location |
Lysosome membrane {ECO:0000305|PubMed:21203937}; Single-pass membrane protein {ECO:0000305|PubMed:21203937}.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:21203937}.
|