Gene Symbol |
ZP4
|
Entrez Gene |
57829
|
Alt Symbol |
ZBP, ZP1, ZPB, Zp-4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
zona pellucida glycoprotein 4
|
Other Description |
zona pellucida B protein|zona pellucida protein B|zona pellucida sperm-binding protein 4
|
Swissprots |
B2RAE1 Q12836
|
Accessions |
AAA74391 EAW70072 Q12836 AK314151 BAG36838 BC069521 AAH69521 BE439656 DV080723 NM_021186 NP_067009
|
Function |
The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor.
|
Subcellular Location |
Processed zona pellucida sperm-binding protein 4: Secreted, extracellular space, extracellular matrix. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida.
|
Tissue Specificity |
Oocytes.
|