| Gene Symbol | GUCY2F |
|---|---|
| Entrez Gene | 2986 |
| Alt Symbol | CYGF, GC-F, GUC2DL, GUC2F, RETGC-2, ROS-GC2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | guanylate cyclase 2F, retinal |
| Other Description | guanylate cyclase 2D-like, membrane (retina-specific)|guanylate cyclase F|retinal guanylyl cyclase 2|rod outer segment membrane guanylate cyclase 2 |
| Swissprots | P51841 Q9UJF1 |
| Accessions | EAX02681 P51841 BC144241 BC156674 AAI56675 L37378 AAA74451 XR_244473 NM_001522 NP_001513 |
| Function | Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Retina. Localized exclusively in the outer nuclear layer and inner segments of the rod and cone photoreceptor cells. |
| Top Pathways | Phototransduction, Purine metabolism |