Gene Symbol | TCP10L |
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Entrez Gene | 140290 |
Alt Symbol | C21orf77, PRED77, TCP10A-2 |
Species | Human |
Gene Type | protein-coding |
Description | t-complex 10-like |
Other Description | T-complex 10A-2|T-complex protein 10A homolog 2|T-complex protein 10A-2|TCP10-like|t-complex 10 (a murine tcp homolog)-like |
Swissprots | Q8N366 Q9NV44 Q8TDR4 Q96LN5 Q53EW0 |
Accessions | EAX09869 Q8TDR4 AF115967 AAM18531 AK001794 BAA91915 AK058078 BAB71653 AK223529 BAD97249 BC022024 BC027970 AAH27970 BC033855 AAH33855 BG717680 BG721020 BI829783 BX111775 CB243926 HG511730 HQ447140 ADQ31627 NM_018277 NM_144659 NP_653260 |
Function | May be involved in transcriptional regulation. Has in vitro transcription inhibition activity. Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells. {ECO:0000269|PubMed:14586771, ECO:0000269|PubMed:24565846}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14586771, ECO:0000269|PubMed:15910542}. |
Tissue Specificity | Expressed in liver and testis. Expressed in the seminiferous tubules (at protein level). {ECO:0000269|PubMed:14586771, ECO:0000269|PubMed:15910542}. |
TCP10L CRISPR/Cas9 KO Plasmid (h) - sc-414478 from Santa Cruz Biotechnology
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TCP10L HDR Plasmid (h) - sc-414478-HDR from Santa Cruz Biotechnology
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TCP10L Double Nickase Plasmid (h) - sc-414478-NIC from Santa Cruz Biotechnology
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TCP10L Double Nickase Plasmid (h2) - sc-414478-NIC-2 from Santa Cruz Biotechnology
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TCP10L CRISPR Activation Plasmid (h) - sc-414478-ACT from Santa Cruz Biotechnology
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TCP10L CRISPR Activation Plasmid (h2) - sc-414478-ACT-2 from Santa Cruz Biotechnology
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TCP10L Lentiviral Activation Particles (h) - sc-414478-LAC from Santa Cruz Biotechnology
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TCP10L Lentiviral Activation Particles (h2) - sc-414478-LAC-2 from Santa Cruz Biotechnology
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TCP10L siRNA (h) - sc-91398 from Santa Cruz Biotechnology
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TCP10L shRNA Plasmid (h) - sc-91398-SH from Santa Cruz Biotechnology
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TCP10L shRNA (h) Lentiviral Particles - sc-91398-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU124991 from Sigma-Aldrich
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MISSION® esiRNA - EHU058141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21164 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21164 from Sigma-Aldrich
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LINC00846 siRNA (Human) - CRJ5272 from Cohesion Biosciences
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TCP10L siRNA (Human) - CRJ5273 from Cohesion Biosciences
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TCP10L - MBS8209597 from MyBioSource
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shRNA set against Human TCP10L (NM_144659.5) - SHH425076 from Creative biogene
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Human TCP10L siRNA - orb275774 from Biorbyt
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Human LINC00846 siRNA - orb275773 from Biorbyt
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LINC00846 shRNA Plasmid (Human) - CHJ5272 from Cohesion Biosciences
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TCP10L shRNA Plasmid (Human) - CHJ5273 from Cohesion Biosciences
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TCP10L miRNA 3'UTR clone - MiUTR3H-09948 from Creative biogene
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