Gene Symbol |
Las
|
Entrez Gene |
40259
|
Alt Symbol |
CG5231, Dmel\CG5231
|
Species |
Drosophila
|
Gene Type |
protein-coding
|
Description |
Lipoic acid synthase
|
Other Description |
CG5231-PC|Las-PC|lipoic acid synthase
|
Swissprots |
Q7JQW6 Q9VPF7
|
Accessions |
AAF51596 Q7JQW6 NM_079459 NP_524183
|
Function |
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}.
|
Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03123}.
|
Top Pathways |
Lipoic acid metabolism
|