Gene Symbol | RNF130 |
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Entrez Gene | 55819 |
Alt Symbol | G1RZFP, GOLIATH, GP |
Species | Human |
Gene Type | protein-coding |
Description | ring finger protein 130 |
Other Description | E3 ubiquitin-protein ligase RNF130|g1-related zinc finger protein|goliath homolog |
Swissprots | Q6P177 J3KN31 Q9P0J9 Q32P32 Q86XS8 Q641P9 Q59EL1 Q7L2U2 |
Accessions | EAW53772 EAW53773 EAW53774 EAW53775 Q86XS8 AA339219 AB209800 BAD93037 AF155650 AAF67007 AK313089 BAG35914 AL515761 AY083998 AAM08686 BC017100 AAH17100 BC065244 AAH65244 BC082267 AAH82267 BC108306 AAI08307 BC113864 AAI13865 BC114472 AAI14473 BP390145 BQ447530 BX404014 DB572650 XM_011534593 XP_011532895 NM_001280801 NP_001267730 NM_018434 NP_060904 |
Function | May have a role during the programmed cell death of hematopoietic cells (By similarity). Acts as an E3 ubiquitin- protein ligase. {ECO:0000250, ECO:0000269|PubMed:16549277}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:16549277}. |
Tissue Specificity | Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts. {ECO:0000269|PubMed:16549277}. |
RNF130 CRISPR/Cas9 KO Plasmid (h) - sc-407535 from Santa Cruz Biotechnology
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RNF130 HDR Plasmid (h) - sc-407535-HDR from Santa Cruz Biotechnology
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RNF130 Double Nickase Plasmid (h) - sc-407535-NIC from Santa Cruz Biotechnology
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RNF130 Double Nickase Plasmid (h2) - sc-407535-NIC-2 from Santa Cruz Biotechnology
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RNF130 CRISPR Activation Plasmid (h) - sc-407535-ACT from Santa Cruz Biotechnology
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RNF130 CRISPR Activation Plasmid (h2) - sc-407535-ACT-2 from Santa Cruz Biotechnology
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RNF130 Lentiviral Activation Particles (h) - sc-407535-LAC from Santa Cruz Biotechnology
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RNF130 Lentiviral Activation Particles (h2) - sc-407535-LAC-2 from Santa Cruz Biotechnology
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RNF130 siRNA (h) - sc-91644 from Santa Cruz Biotechnology
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RNF130 shRNA Plasmid (h) - sc-91644-SH from Santa Cruz Biotechnology
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RNF130 shRNA (h) Lentiviral Particles - sc-91644-V from Santa Cruz Biotechnology
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RNF130 RNAi - H00055819-R01 from Novus Biologicals
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MISSION® esiRNA - EHU019441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18380 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18380 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00675 from Sigma-Aldrich
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RNF130 siRNA (Human) - CRJ0948 from Cohesion Biosciences
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RNF130 - MBS8204631 from MyBioSource
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shRNA set against Human RNF130 (NM_018434.4) - SHH396692 from Creative biogene
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shRNA set against Human RNF130(NM_018434.4) - SHR185240 from Creative biogene
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Human RNF130 siRNA - orb271449 from Biorbyt
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RNF130 shRNA Plasmid (Human) - CHJ0948 from Cohesion Biosciences
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RNF130 miRNA 3'UTR clone - MiUTR1H-08876 from Creative biogene
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