| Gene Symbol | IL18 |
|---|---|
| Entrez Gene | 3606 |
| Alt Symbol | IGIF, IL-18, IL-1g, IL1F4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | interleukin 18 |
| Other Description | IFN-gamma-inducing factor|IL-1 gamma|iboctadekin|interleukin 18 (interferon-gamma-inducing factor)|interleukin-1 gamma|interleukin-18 |
| Swissprots | Q6WWJ7 O75599 Q6FGY3 Q14116 |
| Accessions | ACA06006 CAC01436 EAW67184 EAW67185 Q14116 AF077611 AAC27787 AF380360 AAK57024 AK311301 AY044641 AAK95950 AY266351 AAP92112 BC007007 AAH07007 BC007461 AAH07461 BC015863 BU633686 CR541973 CAG46771 CR542001 CAG46798 D49950 BAA08706 U90434 AAB50010 XM_011542805 XP_011541107 XM_011542806 XP_011541108 NM_001243211 NP_001230140 NM_001562 NP_001553 |
| Function | Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. |
| Subcellular Location | Secreted. |
| Top Pathways | Inflammatory bowel disease (IBD), Cytokine-cytokine receptor interaction, Legionellosis, Tuberculosis, Salmonella infection |