Gene Symbol | IL18 |
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Entrez Gene | 3606 |
Alt Symbol | IGIF, IL-18, IL-1g, IL1F4 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 18 |
Other Description | IFN-gamma-inducing factor|IL-1 gamma|iboctadekin|interleukin 18 (interferon-gamma-inducing factor)|interleukin-1 gamma|interleukin-18 |
Swissprots | Q6WWJ7 O75599 Q6FGY3 Q14116 |
Accessions | ACA06006 CAC01436 EAW67184 EAW67185 Q14116 AF077611 AAC27787 AF380360 AAK57024 AK311301 AY044641 AAK95950 AY266351 AAP92112 BC007007 AAH07007 BC007461 AAH07461 BC015863 BU633686 CR541973 CAG46771 CR542001 CAG46798 D49950 BAA08706 U90434 AAB50010 XM_011542805 XP_011541107 XM_011542806 XP_011541108 NM_001243211 NP_001230140 NM_001562 NP_001553 |
Function | Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. |
Subcellular Location | Secreted. |
Top Pathways | Inflammatory bowel disease (IBD), Cytokine-cytokine receptor interaction, Legionellosis, Tuberculosis, Salmonella infection |
IL-18 CRISPR/Cas9 KO Plasmid (h) - sc-416498 from Santa Cruz Biotechnology
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IL-18 HDR Plasmid (h) - sc-416498-HDR from Santa Cruz Biotechnology
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IL-18 Double Nickase Plasmid (h) - sc-416498-NIC from Santa Cruz Biotechnology
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IL-18 Double Nickase Plasmid (h2) - sc-416498-NIC-2 from Santa Cruz Biotechnology
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IL-18 CRISPR Activation Plasmid (h) - sc-416498-ACT from Santa Cruz Biotechnology
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IL-18 CRISPR Activation Plasmid (h2) - sc-416498-ACT-2 from Santa Cruz Biotechnology
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IL-18 Lentiviral Activation Particles (h) - sc-416498-LAC from Santa Cruz Biotechnology
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IL-18 Lentiviral Activation Particles (h2) - sc-416498-LAC-2 from Santa Cruz Biotechnology
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IL-18 siRNA (h) - sc-39657 from Santa Cruz Biotechnology
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IL-18 shRNA Plasmid (h) - sc-39657-SH from Santa Cruz Biotechnology
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IL-18 shRNA (h) Lentiviral Particles - sc-39657-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU021381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1999 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1999 from Sigma-Aldrich
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IL18 siRNA (Human) - CRH2413 from Cohesion Biosciences
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IL18 - MBS8223028 from MyBioSource
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shRNA set against Human IL18 (NM_001562.3) - SHH318417 from Creative biogene
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Human IL18 siRNA - orb262915 from Biorbyt
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IL18 shRNA Plasmid (Human) - CHH2413 from Cohesion Biosciences
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IL18 miRNA 3'UTR clone - MiUTR3H-03766 from Creative biogene
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