Gene Symbol | GLMN |
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Entrez Gene | 11146 |
Alt Symbol | FAP, FAP48, FAP68, FKBPAP, GLML, GVM, VMGLOM |
Species | Human |
Gene Type | protein-coding |
Description | glomulin, FKBP associated protein |
Other Description | FK506-binding protein-associated protein|FKBP-associated protein|glomulin |
Swissprots | Q9BVE8 Q5VVC3 Q92990 |
Accessions | CAC88124 EAW73097 EAW73098 Q92990 AJ302735 CAC82938 AJ347709 CAC69882 AK295971 BAG58747 BC001257 AAH01257 BG187128 DA729622 U73704 AAC50908 XM_005270400 XP_005270457 XM_005270401 XP_005270458 XM_006710309 XP_006710372 XM_011540544 XP_011538846 XM_011540545 XP_011538847 XM_011540546 XP_011538848 XR_946529 NM_053274 NP_444504 NM_007070 |
Function | Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. Isoform 1 may stimulate the p70S6K pathway. Isoform 2 may inhibit cell proliferation and increase IL2 production. {ECO:0000269|PubMed:11571281, ECO:0000269|PubMed:12604780}. |
Tissue Specificity | Ubiquitous. |
Glomulin CRISPR/Cas9 KO Plasmid (h) - sc-411574 from Santa Cruz Biotechnology
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Glomulin HDR Plasmid (h) - sc-411574-HDR from Santa Cruz Biotechnology
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Glomulin Double Nickase Plasmid (h) - sc-411574-NIC from Santa Cruz Biotechnology
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Glomulin Double Nickase Plasmid (h2) - sc-411574-NIC-2 from Santa Cruz Biotechnology
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Glomulin CRISPR Activation Plasmid (h) - sc-411574-ACT from Santa Cruz Biotechnology
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Glomulin CRISPR Activation Plasmid (h2) - sc-411574-ACT-2 from Santa Cruz Biotechnology
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Glomulin Lentiviral Activation Particles (h) - sc-411574-LAC from Santa Cruz Biotechnology
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Glomulin Lentiviral Activation Particles (h2) - sc-411574-LAC-2 from Santa Cruz Biotechnology
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Glomulin siRNA (h) - sc-45356 from Santa Cruz Biotechnology
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Glomulin shRNA Plasmid (h) - sc-45356-SH from Santa Cruz Biotechnology
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Glomulin shRNA (h) Lentiviral Particles - sc-45356-V from Santa Cruz Biotechnology
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GLMN RNAi - H00011146-R01 from Novus Biologicals
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Fibroblast Activation Protein alpha/FAP RNAi - H00002191-R01 from Novus Biologicals
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MISSION® esiRNA - EHU063721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9350 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9350 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11938 from Sigma-Aldrich
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GLMN siRNA (Human) - CRH7628 from Cohesion Biosciences
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GLMN - MBS8205740 from MyBioSource
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shRNA set against Human GLMN (NM_053274.2) - SHH301854 from Creative biogene
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Human GLMN siRNA - orb268130 from Biorbyt
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GLMN shRNA Plasmid (Human) - CHH7628 from Cohesion Biosciences
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GLMN miRNA 3'UTR clone - MiUTR1H-04068 from Creative biogene
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