| Gene Symbol |
VPS18
|
| Entrez Gene |
57617
|
| Alt Symbol |
PEP3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vacuolar protein sorting 18 homolog (S. cerevisiae)
|
| Other Description |
hVPS18|vacuolar protein sorting protein 18|vacuolar protein sorting-associated protein 18 homolog
|
| Swissprots |
Q8TCG0 Q9P253 Q96DI3 Q9H268
|
| Accessions |
EAW92461 EAW92462 EAW92463 EAW92464 EAW92465 Q9P253 AB040908 BAA95999 AF308802 AAG34679 AL713725 CAD28515 BC001513 AAH01513 DQ892752 ABM83678 DQ895998 ABM86974 XM_011521843 XP_011520145 XM_011521844 XP_011520146 NM_020857 NP_065908
|
| Function |
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. {ECO:0000269|PubMed:11382755}.
|
| Subcellular Location |
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.
|
| Tissue Specificity |
Ubiquitous. Expression was highest in heart and low in lung. {ECO:0000269|PubMed:11382755}.
|
![Western Blot: VPS18 Overexpression Lysate (Adult Normal) [NBL1-17737] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VPS18.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6289_VPS18%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17737-img0002.jpg)