| Gene Symbol |
TDRD12
|
| Entrez Gene |
91646
|
| Alt Symbol |
ECAT8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tudor domain containing 12
|
| Other Description |
ES cell associated transcript 8|ES cell-associated transcript 8 protein|putative ATP-dependent RNA helicase TDRD12|tudor domain-containing protein 12
|
| Swissprots |
Q587J7
|
| Accessions |
Q587J7 AB211063 BAD95490 AK023134 BC049000 BC148519 AAI48520 BI769394 XM_011527471 XP_011525773 XM_011527472 XP_011525774 XM_011527473 XP_011525775 XM_011527474 XP_011525776 XM_011527475 XP_011525777 XM_011527476 XP_011525778 XM_011527477 XP_011525779 NM_001015890 NM_001110822 NP_001104292
|
| Function |
Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process (By similarity). {ECO:0000250}.
|