Gene Symbol | DUSP21 |
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Entrez Gene | 63904 |
Alt Symbol | LMWDSP21 |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 21 |
Other Description | BJ-HCC-26 tumor antigen|LMW-DSP21|dual specificity protein phosphatase 21|low molecular weight dual specificity phosphatase 21 |
Swissprots | Q9H596 Q6YDQ8 Q6IAJ6 Q0VDA6 |
Accessions | EAW59369 Q9H596 AA813372 AF143321 AAD33910 AF533018 AAN59788 AY121807 AAM82755 AY156515 AAO17295 BC119755 AAI19756 BC119756 AAI19757 CR457159 CAG33440 NM_022076 NP_071359 |
Function | Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12408986}. Nucleus {ECO:0000269|PubMed:12408986}. Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}. |
Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:12408986}. |
DUSP21 CRISPR/Cas9 KO Plasmid (h) - sc-412959 from Santa Cruz Biotechnology
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DUSP21 HDR Plasmid (h) - sc-412959-HDR from Santa Cruz Biotechnology
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DUSP21 Double Nickase Plasmid (h) - sc-412959-NIC from Santa Cruz Biotechnology
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DUSP21 Double Nickase Plasmid (h2) - sc-412959-NIC-2 from Santa Cruz Biotechnology
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DUSP21 CRISPR Activation Plasmid (h) - sc-412959-ACT from Santa Cruz Biotechnology
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DUSP21 CRISPR Activation Plasmid (h2) - sc-412959-ACT-2 from Santa Cruz Biotechnology
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DUSP21 Lentiviral Activation Particles (h) - sc-412959-LAC from Santa Cruz Biotechnology
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DUSP21 Lentiviral Activation Particles (h2) - sc-412959-LAC-2 from Santa Cruz Biotechnology
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DUSP21 siRNA (h) - sc-77200 from Santa Cruz Biotechnology
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DUSP21 shRNA Plasmid (h) - sc-77200-SH from Santa Cruz Biotechnology
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DUSP21 shRNA (h) Lentiviral Particles - sc-77200-V from Santa Cruz Biotechnology
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MISSION® Human Phosphatase - SIHP0122 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0123 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2485 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2485 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00788 from Sigma-Aldrich
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DUSP21 siRNA (Human) - CRJ1853 from Cohesion Biosciences
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DUSP21 - MBS8204804 from MyBioSource
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shRNA set against Human Dusp21 (NM_022076.3) - SHH281793 from Creative biogene
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Human DUSP21 siRNA - orb272354 from Biorbyt
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DUSP21 shRNA Plasmid (Human) - CHJ1853 from Cohesion Biosciences
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DUSP21 miRNA 3'UTR clone - MiUTR4H-TG11100 from Creative biogene
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