HGF
| Gene Symbol | HGF |
|---|---|
| Entrez Gene | 3082 |
| Alt Symbol | DFNB39, F-TCF, HGFB, HPTA, SF |
| Species | Human |
| Gene Type | protein-coding |
| Description | hepatocyte growth factor (hepapoietin A; scatter factor) |
| Other Description | fibroblast-derived tumor cytotoxic factor|hepatocyte growth factor|hepatopoeitin-A|hepatopoietin-A|lung fibroblast-derived mitogen |
| Swissprots | Q9BYL9 Q02935 Q9BYM0 A1L3U6 Q3KRB2 Q13494 Q14519 Q9UDU6 P14210 Q8TCE2 |
| Accessions | AAC71655 AAG53459 AAG53460 AAO61091 BAA14348 CAD38058 EAL24189 EAW76992 EAW76993 P14210 AB208900 BAD92137 AK291674 BAF84363 AK313694 BC022308 AAH22308 BC063485 AAH63485 BC105797 AAI05798 BC130284 AAI30285 BC130286 AAI30287 BM153501 BM971901 BU533235 FJ830861 ACX45437 FJ830862 ACX45438 HQ258511 ADR83265 L02931 AAA52649 M29145 AAA52650 M55379 M60718 AAA52648 M73239 AAA64239 M73240 AAA64297 M77227 AAA35980 U46010 AAC50539 X16323 CAA34387 X57574 CAA40802 XM_006715956 XP_006716019 XM_011516115 XP_011514417 NM_000601 NP_000592 NM_001010931 NP_001010931 NM_001010932 NP_001010932 NM_001010933 NP_001010933 NM_001010934 NP_001010934 |
| Function | Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. {ECO:0000269|PubMed:15167892, ECO:0000269|PubMed:20624990}. |
| Top Pathways | Malaria, Proteoglycans in cancer, Rap1 signaling pathway, PI3K-Akt signaling pathway, Cytokine-cytokine receptor interaction |
HGF CRISPR/Cas9 KO Plasmid (h) - sc-400433 from Santa Cruz Biotechnology
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HGF HDR Plasmid (h) - sc-400433-HDR from Santa Cruz Biotechnology
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HGF Double Nickase Plasmid (h) - sc-400433-NIC from Santa Cruz Biotechnology
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HGF Double Nickase Plasmid (h2) - sc-400433-NIC-2 from Santa Cruz Biotechnology
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HGF CRISPR Activation Plasmid (h) - sc-400433-ACT from Santa Cruz Biotechnology
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HGF CRISPR Activation Plasmid (h2) - sc-400433-ACT-2 from Santa Cruz Biotechnology
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HGF Lentiviral Activation Particles (h) - sc-400433-LAC from Santa Cruz Biotechnology
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HGF Lentiviral Activation Particles (h2) - sc-400433-LAC-2 from Santa Cruz Biotechnology
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HGFα/β siRNA (h) - sc-37111 from Santa Cruz Biotechnology
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HGFα/β shRNA Plasmid (h) - sc-37111-SH from Santa Cruz Biotechnology
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HGFα/β shRNA (h) Lentiviral Particles - sc-37111-V from Santa Cruz Biotechnology
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HGF RNAi - H00003082-R01 from Novus Biologicals
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HGF RNAi - H00003082-R05 from Novus Biologicals
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HGF RNAi - H00003082-R04 from Novus Biologicals
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HGF RNAi - H00003082-R03 from Novus Biologicals
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HGF RNAi - H00003082-R02 from Novus Biologicals
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MISSION® esiRNA - EHU134811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1758 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1758 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08915 from Sigma-Aldrich
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HGF siRNA (Human) - CRH2100 from Cohesion Biosciences
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HGF - MBS8220250 from MyBioSource
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shRNA set against Human Hgf (NM_000601.4) - SHH311909 from Creative biogene
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shRNA set against Human HGF(NM_000601.4) - SHH119773 from Creative biogene
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shRNA set against Human HGF(NM_001010933.1) - SHH119801 from Creative biogene
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