Zfand5

Gene Symbol Zfand5
Entrez Gene 22682
Alt Symbol 2310057A04Rik, 5830475F03Rik, AA415485, Za20d2, Zfp216
Species Mouse
Gene Type protein-coding
Description zinc finger, AN1-type domain 5
Other Description AN1-type zinc finger protein 5|zinc finger A20 domain-containing protein 2|zinc finger protein 216|zinc finger, A20 domain containing 2
Swissprots Q3B7K8 O88878
Accessions EDL41583 O88878 AF062071 AAC42600 AK009947 AK018054 AK039663 AK046445 AK076397 BAC36321 AK131911 AK185148 AK186976 AK211340 AK216435 AK218278 BC048232 BC061693 BC080270 BC107566 AAI07567 BC119124 AAI19125 BC119126 AAI19127 EF437362 L37047 XM_006527058 XP_006527121 NM_009551 NP_033577
Function Involved in protein degradation via the ubiquitin- proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4- induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. {ECO:0000269|PubMed:16194934, ECO:0000269|PubMed:16424905}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Expressed in brain, muscle, eye, and heart, lower expression in lung, kidney, and spleen, and very low expression in liver. Expressed in myoblast C2C12 cells (at protein level). {ECO:0000269|PubMed:14754897, ECO:0000269|PubMed:9758550}.

ZNF216 CRISPR/Cas9 KO Plasmid (m) - sc-423772 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ZNF216 HDR Plasmid (m) - sc-423772-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ZNF216 Double Nickase Plasmid (m) - sc-423772-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ZNF216 Double Nickase Plasmid (m2) - sc-423772-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ZNF216 CRISPR Activation Plasmid (m) - sc-423772-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ZNF216 CRISPR Activation Plasmid (m2) - sc-423772-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ZNF216 Lentiviral Activation Particles (m) - sc-423772-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ZNF216 Lentiviral Activation Particles (m2) - sc-423772-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ZNF216 siRNA (m) - sc-155657 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

ZNF216 shRNA Plasmid (m) - sc-155657-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

ZNF216 shRNA (m) Lentiviral Particles - sc-155657-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU031661 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN44920 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND44920 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ZFAND5 siRNA (Mouse) - CRM4479 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

ZFAND5 - MBS8231974 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse ZFAND5 (NM_009551.5) - SHH450200 from Creative biogene

Category siRNA
Species Reactivities Mouse

ZFAND5 shRNA Plasmid (Mouse) - CHM4479 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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