| Gene Symbol |
CXXC5
|
| Entrez Gene |
51523
|
| Alt Symbol |
CF5, HSPC195, RINF, WID
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CXXC finger protein 5
|
| Other Description |
CXXC finger 5 protein|CXXC-type zinc finger protein 5|WT1-induced Inhibitor of Dishevelled|putative MAPK-activating protein PM08|putative NF-kappa-B-activating protein 102|retinoid-inducible nuclear factor
|
| Swissprots |
Q9P0S8 Q8TB79 Q7LFL8 Q9NV51 C8CBA8 B3KND0
|
| Accessions |
CAE92164 EAW62090 EAW62091 EAW62092 EAW62093 Q7LFL8 AB097005 BAC77358 AB097032 BAC77385 AF151029 AAF36115 AK001782 BAA91907 AK024338 BAG51292 AK314420 AY007103 AAG01986 BC002490 AAH02490 BC006428 AAH06428 BC017439 AAH17439 BC024040 AAH24040 BC041013 AAH41013 BC050046 DQ892589 ABM83515 DQ895807 ABM86733 GQ379202 ACU80469 XM_005268461 XP_005268518 XM_005268462 XP_005268519 XM_006714786 XP_006714849 NM_016463 NP_057547
|
| Function |
May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. {ECO:0000250, ECO:0000269|PubMed:19182210, ECO:0000269|PubMed:19557330}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:19182210, ECO:0000269|PubMed:19557330}. Cytoplasm {ECO:0000250}. Note=Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane. {ECO:0000250}.
|
![Western Blot: CXXC5 Overexpression Lysate (Adult Normal) [NBP2-07032] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CXXC5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4786_CXXC5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07032-img0001.jpg)