DAZAP1
| Gene Symbol | DAZAP1 |
|---|---|
| Entrez Gene | 26528 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | DAZ associated protein 1 |
| Other Description | DAZ-associated protein 1|deleted in azoospermia-associated protein 1 |
| Swissprots | Q96EP5 Q9NRR9 Q96MJ3 |
| Accessions | AAW01463 CBF67654 CBU92528 EAW69501 EAW69502 EAW69503 EAW69504 Q96EP5 AF181719 AAF78364 AI802551 AK056850 BAB71295 AK092894 BAG52625 AK124583 AK125032 AK128682 AL360261 BC012062 AAH12062 BI909277 BU557183 EU446950 ABZ92479 XM_005259531 XP_005259588 XM_005259534 XP_005259591 XM_005259535 XP_005259592 XM_005259536 XP_005259593 XM_011527904 XP_011526206 XM_011527905 XP_011526207 XM_011527906 XP_011526208 XM_011527907 XP_011526209 XM_011527908 XP_011526210 XM_011527909 XP_011526211 XM_011527910 XP_011526212 NM_018959 NP_061832 NM_170711 NP_733829 |
| Function | RNA-binding protein, which may be required during spermatogenesis. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:22001406}. Nucleus {ECO:0000269|PubMed:22001406}. Note=Predominantly cytoplasmic (By similarity). Nuclear at some stages of spermatozoides development. In midpachytene spermatocytes, it is localized in both the cytoplasm and the nuclei and is clearly excluded from the sex vesicles. In round spermatids, it localizes mainly in the nuclei, whereas in elongated spermatids, it localizes to the cytoplasm (By similarity). {ECO:0000250}. |
| Tissue Specificity | Mainly expressed in testis. Expressed to a lower level in thymus. Weakly or not expressed in heart, liver, brain, placenta, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10857750}. |
| Top Pathways | mRNA surveillance pathway |
DAZAP1 CRISPR/Cas9 KO Plasmid (h) - sc-404672 from Santa Cruz Biotechnology
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DAZAP1 HDR Plasmid (h) - sc-404672-HDR from Santa Cruz Biotechnology
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DAZAP1 Double Nickase Plasmid (h) - sc-404672-NIC from Santa Cruz Biotechnology
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DAZAP1 Double Nickase Plasmid (h2) - sc-404672-NIC-2 from Santa Cruz Biotechnology
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DAZAP1 CRISPR Activation Plasmid (h) - sc-404672-ACT from Santa Cruz Biotechnology
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DAZAP1 CRISPR Activation Plasmid (h2) - sc-404672-ACT-2 from Santa Cruz Biotechnology
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DAZAP1 Lentiviral Activation Particles (h) - sc-404672-LAC from Santa Cruz Biotechnology
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DAZAP1 Lentiviral Activation Particles (h2) - sc-404672-LAC-2 from Santa Cruz Biotechnology
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DAZAP1 siRNA (h) - sc-62194 from Santa Cruz Biotechnology
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DAZAP1 shRNA Plasmid (h) - sc-62194-SH from Santa Cruz Biotechnology
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DAZAP1 shRNA (h) Lentiviral Particles - sc-62194-V from Santa Cruz Biotechnology
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DAZAP1 RNAi - H00026528-R02 from Novus Biologicals
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MISSION® esiRNA - EHU076441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6939 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6939 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13049 from Sigma-Aldrich
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DAZAP1 siRNA (Human) - CRH8851 from Cohesion Biosciences
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DAZAP1 RNAi - H00026528-R01 from Novus Biologicals
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DAZAP1 - MBS8211797 from MyBioSource
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shRNA set against Human DAZAP1 (NM_018959.2) - SHH274649 from Creative biogene
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shRNA set against Human DAZAP1(NM_170711.1) - SHG222097 from Creative biogene
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shRNA set against Human DAZAP1(NM_018959.2) - SHG222207 from Creative biogene
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shRNA set against Human DAZAP1(NM_170711.1) - SHG222225 from Creative biogene
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DAZAP1 shRNA Plasmid (Human) - CHH8851 from Cohesion Biosciences
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DAZAP1 miRNA 3'UTR clone - MiUTR1H-02671 from Creative biogene
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