| Gene Symbol | CHRNB2 |
|---|---|
| Entrez Gene | 1141 |
| Alt Symbol | EFNL3, nAChRB2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| Other Description | acetylcholine receptor, nicotinic, beta 2 (neuronal)|beta2 human neuronal nicotinic acetylcholine receptor|cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)|neuronal acetylcholine receptor subunit beta-2|neuronal nicotinic acetylcholine receptor beta 2 |
| Swissprots | Q9UEH9 P17787 |
| Accessions | AAD45422 CAA05108 CAD88996 EAW53192 P17787 AK313470 BAG36255 BC075040 AAH75040 BC075041 AAH75041 R40506 U62437 AAB40115 X53179 CAA37320 Y08415 CAA69692 NM_000748 NP_000739 |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions. {ECO:0000269|PubMed:22361591}. |
| Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Top Pathways | Nicotine addiction, Neuroactive ligand-receptor interaction |