| Gene Symbol |
MTMR14
|
| Entrez Gene |
64419
|
| Alt Symbol |
C3orf29
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myotubularin related protein 14
|
| Other Description |
HCV NS5A-transactivated protein 4 splice variant A-binding protein 1|NS5ATP4ABP1|egg-derived tyrosine phosphatase homolog|jumpy|myotubularin-related protein 14
|
| Swissprots |
Q8NCE2 Q0JU83 Q6PIZ4 Q6QE21 Q8IYK1 Q0JTH5 Q86VK9 Q9H6C0 Q8TCM7
|
| Accessions |
EAW63965 EAW63966 EAW63967 EAW63968 EAW63969 Q8NCE2 AF289603 AAL55787 AK021608 AK026058 BAB15340 AK074792 BAC11211 AK128312 AK295891 BAG58685 AK298846 BAG60971 AL713695 CAD28494 AY007098 AY545552 AAS50151 BC001674 AAH01674 BC025952 AAH25952 BC035690 AAH35690 BC050626 AAH50626 BF796406 DA604126 DC316206 DQ630520 ABG02221 EU832316 ACE87573 EU832401 ACE86886 XM_005265400 XP_005265457 XM_011534012 XP_011532314 XM_011534013 XP_011532315 XR_245152 NM_001077525 NP_001070993 NM_001077526 NP_001070994 NM_022485 NP_071930
|
| Function |
Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3. {ECO:0000269|PubMed:17008356}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17008356}. Note=Found in reticular structures and plasma membrane ruffles. Concentrated near the nucleus.
|
| Tissue Specificity |
Expressed in various tissues, including heart, skeletal muscle, placenta, liver, lung, kidney and pancreas. {ECO:0000269|PubMed:17008356}.
|