Gene Symbol | HBB |
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Entrez Gene | 3043 |
Alt Symbol | CD113t-C, beta-globin |
Species | Human |
Gene Type | protein-coding |
Description | hemoglobin, beta |
Other Description | beta globin chain|hemoglobin beta chain|hemoglobin subunit beta |
Swissprots | Q9UCD6 Q13852 P02023 Q6FI08 Q45KT0 A4GX73 Q14510 Q8IZI1 Q9BX96 P68871 Q9UCP8 Q9UCP9 Q549N7 Q14481 Q6R7N2 B2ZUE0 |
Accessions | AAA16334 AAA16335 AAA21100 AAA21101 AAA21102 AAA21103 AAA21104 AAA21105 AAA21106 AAA21107 AAA21108 AAA21109 AAA21110 AAA21111 AAA21112 AAA21113 AAA21114 AAA21115 AAA21116 AAA35952 AAA52634 AAA52635 AAA53153 AAA88052 AAA88054 AAA88055 AAA88057 AAA88059 AAA88061 AAA88063 AAA88065 AAA88067 AAA88068 AAA88069 AAA99224 AAB60348 AAB62944 AAC97372 AAC97959 AAD14211 AAD14420 AAD30656 AAD34034 AAF08258 AAF08259 AAF08260 AAF08261 AAF08262 AAF08263 AAF08264 AAF08265 AAF08266 AAF08267 AAF08268 AAF08269 AAF08270 AAF08271 AAF08272 AAG28778 AAG28779 AAG46182 AAG46183 AAG46184 AAG46185 AAK15811 AAK20080 AAK28064 AAK28065 AAK28066 AAK30154 AAK39553 AAL68978 AAM92001 AAN11321 AAN16468 AAN84548 AAP03091 AAP21062 AAP44006 AAP74754 AAQ24847 AAQ24848 AAQ63175 AAT36650 AAT36651 AAU85261 AAW66689 AAY15222 AAY46275 AAY51976 AAY84735 AAZ22545 AAZ30391 AAZ39745 AAZ39746 AAZ39747 AAZ39748 AAZ39749 AAZ39750 AAZ39751 AAZ39752 AAZ39753 AAZ39754 AAZ39755 AAZ39756 AAZ39757 AAZ39758 AAZ39759 AAZ39760 AAZ39761 AAZ39762 AAZ39763 AAZ39764 AAZ39765 AAZ39766 AAZ39767 AAZ39768 AAZ39769 AAZ39770 AAZ39771 AAZ39772 AAZ39773 AAZ39774 AAZ39775 AAZ39776 AAZ39777 AAZ39778 AAZ39779 AAZ39780 AAZ39781 AAZ39782 AAZ39783 AAZ39784 AAZ39785 AAZ39786 AAZ39787 AAZ39788 AAZ39789 AAZ39790 AAZ39791 AAZ39792 AAZ39793 AAZ39794 AAZ39795 AAZ39796 AAZ39797 AAZ39798 AAZ39799 AAZ39800 AAZ81986 ABA19233 ABB82620 ABG47031 ABL84269 ABO36678 ABY26552 ACC69180 ACC69181 ACC78290 ACE80932 ACF16747 ACF16748 ACF16749 ACF16750 ACF16751 ACF16752 ACF16753 ACF16754 ACF16755 ACF16756 ACF16757 ACF16758 ACF16759 ACF16760 ACF16761 ACF16762 ACF16763 ACF16764 ACF16765 ACF16766 ACF16767 ACF16768 ACF16769 ACF16770 ACF16771 ACF16772 ACF16773 ACF16774 ACF16775 ACF16776 ACF16777 ACF16778 ACF16779 ACF16780 ACF16781 ACF16782 ACF16783 ACF16784 ACF16785 ACF16786 ACF16787 ACF16788 ACF16789 ACF16790 ACF16791 ACF16792 ACF16793 ACF16794 ACF16795 ACF93730 ACU56984 ACZ67952 ACZ67953 ADL14493 ADV59922 ADW79453 AEQ28038 AFR11469 AFV63186 AFV63187 AJW81992 AJW81993 AJW81994 AJW81995 AJW81996 AJW81997 AJW81998 AJW81999 AJW82000 AJW82001 AJW82002 AJW82003 AJW82004 AJW82005 AJW82006 AJW82007 AJW82008 AJW82009 AJW82010 CAA00182 CAA23757 CAA23758 CAI40296 CAI47563 CAX48890 CAX48956 CAY85982 CDH61667 EAW68806 P68871 AF117710 AAD19696 AF181832 AAF00488 AF181989 AAF00489 AF349114 AAK29639 AK311825 BAG34767 AM392537 CAL37415 AM393351 CAL38229 AY136510 AAN11320 AY509193 AAR96398 BC007075 AAH07075 CR536530 CAG38767 CR541913 CAG46711 DQ655983 DQ893159 ABM84085 DQ896453 ABM87452 EU176774 ABW03575 EU694432 ACD39349 M11428 AAA52633 M14574 M25079 AAA35597 M25113 AAA35966 V00497 CAA23756 V00500 CAA23759 NM_000518 NP_000509 |
Function | Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation. |
Tissue Specificity | Red blood cells. {ECO:0000269|PubMed:6539334}. |
Top Pathways | Malaria, African trypanosomiasis |
Human Hemoglobin A1c full length protein - ab98306 from Abcam
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Human Hemoglobin A1c full length protein - ab82273 from Abcam
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Human Hemoglobin subunit beta protein fragment - ab158639 from Abcam
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HBB / Hemoglobin Beta Blocking Peptide - LS-E1067 from LifeSpan Bioscience
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Recombinant Human Hemoglobin beta Protein - H00003043-Q01 from Novus Biologicals
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HBB-Antibody-C-term-Blocking-peptide - BP11557b from Abgent, a WuXi AppTec company
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Hemoglobin beta Protein - GTX116412-pro from GeneTex
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Human HBB protein - orb246357 from Biorbyt
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Hemoglobin beta chain - H00003043-Q01-10 from Acris Antibodies
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Hemoglobin beta chain - H00003043-Q01-25 from Acris Antibodies
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HBB fusion protein - ag9216 from Proteintech Group
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VV-Hemorphin-5 Peptide - 350584 from ABBIOTEC
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Spinorphin Peptide - 350391 from ABBIOTEC
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LVV-Hemorphin-7 Peptide - 350583 from ABBIOTEC
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Hemorphin-7 Peptide - 350217 from ABBIOTEC
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Hemorphin-7 - GWB-CF3F04 from Genway Biotech
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Recombinant Human HBB, GST-tagged - HBB-13679H from Creative Biomart
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Recombinant Hemoglobin Beta (HBb) - RPD098Hu01 from Uscn Life Science Inc.
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Recombinant Hemoglobin Beta (HBb) - RPD098Mu01 from Uscn Life Science Inc.
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Recombinant Human Hemoglobin subunit beta(HBB) - CSB-YP010150HU CSB-BP010150HU CSB-MP010150HU from Cusabio
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Recombinant human Hemoglobin subunit beta - CSB-EP010150HU from Cusabio
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Recombinant Hemoglobin subunit beta(hbb) - CSB-YP010150AOD CSB-EP010150AOD CSB-BP010150AOD CSB-MP010150AOD from Cusabio
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Hemoglobin beta chain - TP303258 from Acris Antibodies
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Hemoglobin beta Recombinant Protein Antigen - NBP2-14081PEP from Novus Biologicals
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HBB Peptide, Human - M34GP06857H from Creative Peptides
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