| Gene Symbol | INS |
|---|---|
| Entrez Gene | 3630 |
| Alt Symbol | IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10 |
| Species | Human |
| Gene Type | protein-coding |
| Description | insulin |
| Other Description | preproinsulin|proinsulin |
| Swissprots | Q5EEX2 P01308 |
| Accessions | AAA59172 AAA59173 AAA59179 AAN39451 CAA08766 CAA23828 EAX02488 EAX02489 P01308 AY899304 AAW83741 BC005255 AAH05255 BM510347 BM510748 BP322143 BT006808 AAP35454 DQ778082 ABI63346 DQ893040 ABM83966 DQ896283 ABM87282 JF909299 AEG19452 JQ951950 AFK93533 X70508 CAA49913 NM_000207 NP_000198 NM_001185097 NP_001172026 NM_001185098 NP_001172027 NM_001291897 NP_001278826 |
| Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| Subcellular Location | Secreted. |
| Top Pathways | Oocyte meiosis, cGMP-PKG signaling pathway, AMPK signaling pathway, Rap1 signaling pathway, Non-alcoholic fatty liver disease (NAFLD) |