Gene Symbol | INS |
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Entrez Gene | 3630 |
Alt Symbol | IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10 |
Species | Human |
Gene Type | protein-coding |
Description | insulin |
Other Description | preproinsulin|proinsulin |
Swissprots | Q5EEX2 P01308 |
Accessions | AAA59172 AAA59173 AAA59179 AAN39451 CAA08766 CAA23828 EAX02488 EAX02489 P01308 AY899304 AAW83741 BC005255 AAH05255 BM510347 BM510748 BP322143 BT006808 AAP35454 DQ778082 ABI63346 DQ893040 ABM83966 DQ896283 ABM87282 JF909299 AEG19452 JQ951950 AFK93533 X70508 CAA49913 NM_000207 NP_000198 NM_001185097 NP_001172026 NM_001185098 NP_001172027 NM_001291897 NP_001278826 |
Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
Subcellular Location | Secreted. |
Top Pathways | Oocyte meiosis, cGMP-PKG signaling pathway, AMPK signaling pathway, Rap1 signaling pathway, Non-alcoholic fatty liver disease (NAFLD) |
Insulin CRISPR/Cas9 KO Plasmid (h) - sc-400149 from Santa Cruz Biotechnology
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Insulin HDR Plasmid (h) - sc-400149-HDR from Santa Cruz Biotechnology
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Insulin Double Nickase Plasmid (h) - sc-400149-NIC from Santa Cruz Biotechnology
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Insulin Double Nickase Plasmid (h2) - sc-400149-NIC-2 from Santa Cruz Biotechnology
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Insulin CRISPR Activation Plasmid (h) - sc-400149-ACT from Santa Cruz Biotechnology
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Insulin CRISPR Activation Plasmid (h2) - sc-400149-ACT-2 from Santa Cruz Biotechnology
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Insulin Lentiviral Activation Particles (h) - sc-400149-LAC from Santa Cruz Biotechnology
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Insulin Lentiviral Activation Particles (h2) - sc-400149-LAC-2 from Santa Cruz Biotechnology
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Insulin siRNA (h) - sc-39578 from Santa Cruz Biotechnology
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Insulin shRNA Plasmid (h) - sc-39578-SH from Santa Cruz Biotechnology
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Insulin shRNA (h) Lentiviral Particles - sc-39578-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10697 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10697 from Sigma-Aldrich
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INS siRNA (Human) - CRH2433 from Cohesion Biosciences
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INS - MBS8222918 from MyBioSource
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shRNA set against Human INS (NM_000207.2) - SHH319789 from Creative biogene
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INS shRNA Plasmid (Human) - CHH2433 from Cohesion Biosciences
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INS miRNA 3'UTR clone - MiUTR1H-04958 from Creative biogene
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