| Gene Symbol |
OGFOD1
|
| Entrez Gene |
55239
|
| Alt Symbol |
TPA1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
2-oxoglutarate and iron-dependent oxygenase domain containing 1
|
| Other Description |
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1|TPA1, termination and polyadenylation 1, homolog|prolyl 3-hydroxylase OGFOD1|termination and polyadenylation 1 homolog
|
| Swissprots |
Q9NVB6 H3BUQ2 Q9H9J9 Q9HA87 Q9HCG0 Q9H7U5 Q8N543
|
| Accessions |
CCQ43592 EAW82861 EAW82862 Q8N543 AB046832 BAB13438 AK001688 BAA91838 AK022130 BAB13967 AK022752 BAB14226 AK024314 BAB14880 AK304584 BAG65372 AL711389 BC032919 AAH32919 XM_011523198 XP_011521500 NM_018233 NP_060703
|
| Function |
Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit RPS23, thereby regulating protein translation termination efficiency. Involved in stress granule formation. {ECO:0000269|PubMed:20154146, ECO:0000269|PubMed:24550447, ECO:0000269|PubMed:24550462}.
|
| Subcellular Location |
Isoform 1: Cytoplasm. Nucleus. Note=Mainly nuclear. A portion relocalizes to cytoplasmic stress granules upon stress.
|