Gene Symbol | ACSM2A |
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Entrez Gene | 123876 |
Alt Symbol | A-923A4.1, ACSM2 |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA synthetase medium-chain family member 2A |
Other Description | Homolog of rat kidney-specific (KS)|acyl-CoA synthetase medium-chain family member 2|acyl-coenzyme A synthetase ACSM2A, mitochondrial|butyrate--CoA ligase 2A|butyryl-coenzyme A synthetase 2A|middle-chain acyl-CoA synthetase 2A |
Swissprots | Q08AH3 O75202 B3KTT9 |
Accessions | AAC23497 Q08AH3 AI075158 AI340924 AK055867 BAG51587 AK091878 AK091978 BAC03784 AK096039 BAG53201 AK096132 AK298359 BAH12766 AK298434 BAG60655 AK303774 BAH14046 BC125175 BC125176 AAI25177 DA034571 DC361518 DC362857 XM_005255093 XP_005255150 XM_011545733 XP_011544035 XR_243259 NM_001010845 NP_001010845 NM_001308169 NP_001295098 NM_001308172 NP_001295101 |
Function | Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion matrix {ECO:0000250}. |
Top Pathways | Butanoate metabolism |
ACSM2A CRISPR/Cas9 KO Plasmid (h) - sc-414203 from Santa Cruz Biotechnology
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ACSM2A HDR Plasmid (h) - sc-414203-HDR from Santa Cruz Biotechnology
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ACSM2A Double Nickase Plasmid (h) - sc-414203-NIC from Santa Cruz Biotechnology
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ACSM2A Double Nickase Plasmid (h2) - sc-414203-NIC-2 from Santa Cruz Biotechnology
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ACSM2A CRISPR Activation Plasmid (h) - sc-414203-ACT from Santa Cruz Biotechnology
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ACSM2A CRISPR Activation Plasmid (h2) - sc-414203-ACT-2 from Santa Cruz Biotechnology
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ACSM2A Lentiviral Activation Particles (h) - sc-414203-LAC from Santa Cruz Biotechnology
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ACSM2A Lentiviral Activation Particles (h2) - sc-414203-LAC-2 from Santa Cruz Biotechnology
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ACSM2A siRNA (h) - sc-93158 from Santa Cruz Biotechnology
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ACSM2A shRNA Plasmid (h) - sc-93158-SH from Santa Cruz Biotechnology
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ACSM2A shRNA (h) Lentiviral Particles - sc-93158-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN2758 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2758 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07925 from Sigma-Aldrich
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ACSM2A siRNA (Human) - CRJ4744 from Cohesion Biosciences
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ACSM2A - MBS8220879 from MyBioSource
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shRNA set against Human Acsm2 (NM_001010845.2) - SHH230790 from Creative biogene
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Human ACSM2A siRNA - orb275245 from Biorbyt
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ACSM2A shRNA Plasmid (Human) - CHJ4744 from Cohesion Biosciences
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ACSM2A miRNA 3'UTR clone - MiUTR1H-05723 from Creative biogene
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