Gene Symbol | CTPS2 |
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Entrez Gene | 56474 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | CTP synthase 2 |
Other Description | CTP synthase II|CTP synthetase type 2|UTP-ammonia ligase 2|cytidine 5'-triphosphate synthetase 2 |
Swissprots | Q9NRF8 Q9H8K9 Q9H809 B3KWM2 Q9BRI0 |
Accessions | EAW98912 EAW98913 EAW98914 EAW98915 Q9NRF8 AF086422 AF226667 AAF91241 AK023549 BAB14607 AK024070 BAB14814 AK025654 BAB15204 AK125332 BAG54184 AK125348 BAG54188 AK309508 BC006256 AAH06256 BC034986 AAH34986 BX647712 DA741994 DA759070 JF432696 ADZ15913 XM_005274562 XP_005274619 XM_006724503 XP_006724566 XM_011545545 XP_011543847 XM_011545546 XP_011543848 NM_001144002 NP_001137474 NM_019857 NP_062831 NM_175859 NP_787055 |
Function | Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. {ECO:0000269|PubMed:10899599, ECO:0000269|PubMed:16179339}. |
Top Pathways | Pyrimidine metabolism |
CTPS2 CRISPR/Cas9 KO Plasmid (h) - sc-412706 from Santa Cruz Biotechnology
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CTPS2 HDR Plasmid (h) - sc-412706-HDR from Santa Cruz Biotechnology
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CTPS2 Double Nickase Plasmid (h) - sc-412706-NIC from Santa Cruz Biotechnology
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CTPS2 Double Nickase Plasmid (h2) - sc-412706-NIC-2 from Santa Cruz Biotechnology
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CTPS2 CRISPR Activation Plasmid (h) - sc-412706-ACT from Santa Cruz Biotechnology
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CTPS2 CRISPR Activation Plasmid (h2) - sc-412706-ACT-2 from Santa Cruz Biotechnology
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CTPS2 Lentiviral Activation Particles (h) - sc-412706-LAC from Santa Cruz Biotechnology
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CTPS2 Lentiviral Activation Particles (h2) - sc-412706-LAC-2 from Santa Cruz Biotechnology
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CTPS2 siRNA (h) - sc-91001 from Santa Cruz Biotechnology
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CTPS2 shRNA Plasmid (h) - sc-91001-SH from Santa Cruz Biotechnology
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CTPS2 shRNA (h) Lentiviral Particles - sc-91001-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU078091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6743 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6743 from Sigma-Aldrich
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CTPS2 siRNA (Human) - CRJ1141 from Cohesion Biosciences
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CTPS2 - MBS8216649 from MyBioSource
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shRNA set against Human CTPS2 (NM_175859.1) - SHH271393 from Creative biogene
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shRNA set against Human CTPS2(NM_019857.3) - SHG172141 from Creative biogene
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Human CTPS2 siRNA - orb271642 from Biorbyt
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CTPS2 shRNA Plasmid (Human) - CHJ1141 from Cohesion Biosciences
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CTPS2 miRNA 3'UTR clone - MiUTR1H-02536 from Creative biogene
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CTPS2 miRNA 3'UTR clone - MiUTR3H-02723 from Creative biogene
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CTPS2 miRNA 3'UTR clone - MiUTR3H-02725 from Creative biogene
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