Gene Symbol |
LRIF1
|
Entrez Gene |
55791
|
Alt Symbol |
C1orf103, RIF1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ligand dependent nuclear receptor interacting factor 1
|
Other Description |
ligand-dependent nuclear receptor-interacting factor 1|receptor interacting factor 1|receptor-interacting factor 1
|
Swissprots |
Q9NUM5 Q8N3B6 Q96HT4 Q86XS4 Q5T3J3 Q9NV32
|
Accessions |
EAW56460 EAW56461 Q5T3J3 AK001826 BAA91928 AK002131 BAA92097 AL834466 CAD39125 AY190122 AAO43631 BC008115 AAH08115 BQ787643 BU192014 BU664417 CD686306 HQ448282 ADQ32762 XM_005271029 XP_005271086 XM_011541768 XP_011540070 NM_001006945 NP_001006946 NM_018372 NP_060842
|
Function |
Represses the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA). This repression may occur through direct recruitment of histone deacetylases. {ECO:0000269|PubMed:17455211}.
|
Subcellular Location |
Nucleus matrix {ECO:0000269|PubMed:17455211}.
|
Tissue Specificity |
Widely expressed, with the highest expression levels in heart, liver and placenta. {ECO:0000269|PubMed:17455211}.
|