| Gene Symbol |
MAGED4B
|
| Entrez Gene |
81557
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
melanoma antigen family D4B
|
| Other Description |
MAGE-D4 antigen|MAGE-E1 antigen|melanoma antigen family D, 4B|melanoma-associated antigen D4
|
| Swissprots |
Q96JG8 Q9BVH1 Q5HYN6 A8K093 Q8WXW4 Q9BQ84 Q9BYH4 Q9H217 Q9BYH3
|
| Accessions |
BAB61778 BAB61779 BAB61780 CAI41307 EAW62885 EAW62888 EAW62894 Q96JG8 AB040527 BAB33378 AB040528 BAB33379 AB040529 BAB33380 AB058762 BAB47488 AF320908 AAG38604 AF329733 AAL50032 AK094541 AK098830 AK289458 BAF82147 AK308365 AL136582 CAB66517 BC001207 AAH01207 BC063838 AAH63838 BC081566 AAH81566 XM_005276713 XP_005276770 XM_006724607 XP_006724670 XM_006724608 XP_006724671 XM_006726845 XP_006726908 XM_011530822 XP_011529124 XM_011530823 XP_011529125 NM_001242362 NP_001229291 NM_030801 NP_110428 NM_177535 NP_803879 NM_177537 NP_803881
|
| Function |
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. {ECO:0000269|PubMed:20864041}.
|
| Tissue Specificity |
Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are specifically expressed in glioma cells among cancer cells. Detected in some renal cell carcinoma samples. {ECO:0000269|PubMed:11406556, ECO:0000269|PubMed:16082191}.
|
![Western Blot: MAGED4B Overexpression Lysate (Adult Normal) [NBP2-06179] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MAGED4B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6729_MAGED4B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06179-img0001.jpg)
![Western Blot: MAGED4B Overexpression Lysate (Adult Normal) [NBL1-12817] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MAGED4B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4030_MAGED4B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12817-img0002.jpg)