Gene Symbol | MMP27 |
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Entrez Gene | 64066 |
Alt Symbol | MMP-27 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 27 |
Other Description | matrix metalloprotease 27|matrix metalloproteinase 27|matrix metalloproteinase-27 |
Swissprots | Q9H306 Q6UWK6 |
Accessions | EAW67026 Q9H306 AF195192 AAG28453 AY358752 AAQ89112 BC140433 AAI40434 BX102293 XM_011542948 XP_011541250 XM_011542949 XP_011541251 XM_011542950 XP_011541252 XM_011542951 XP_011541253 NM_022122 NP_071405 |
Function | Matrix metalloproteinases degrade protein components of the extracellular matrix such as fibronectin, laminin, gelatins and/or collagens. {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein {ECO:0000269|PubMed:24548619}. Note=Retained in the endoplasmic reticulum. {ECO:0000269|PubMed:24548619}. |
Tissue Specificity | Expressed in B-cells (PubMed:14506071). Expressed in a subset of endometrial macrophages related to menstruation and in ovarian and peritoneal endometriotic lesions (at protein level)(PubMed:24810263). {ECO:0000269|PubMed:14506071, ECO:0000269|PubMed:24810263}. |
MMP-27 CRISPR/Cas9 KO Plasmid (h) - sc-410088 from Santa Cruz Biotechnology
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MMP-27 HDR Plasmid (h) - sc-410088-HDR from Santa Cruz Biotechnology
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MMP-27 Double Nickase Plasmid (h) - sc-410088-NIC from Santa Cruz Biotechnology
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MMP-27 Double Nickase Plasmid (h2) - sc-410088-NIC-2 from Santa Cruz Biotechnology
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MMP-27 CRISPR Activation Plasmid (h) - sc-410088-ACT from Santa Cruz Biotechnology
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MMP-27 CRISPR Activation Plasmid (h2) - sc-410088-ACT-2 from Santa Cruz Biotechnology
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MMP-27 Lentiviral Activation Particles (h) - sc-410088-LAC from Santa Cruz Biotechnology
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MMP-27 Lentiviral Activation Particles (h2) - sc-410088-LAC-2 from Santa Cruz Biotechnology
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MMP-27 siRNA (h) - sc-96557 from Santa Cruz Biotechnology
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MMP-27 shRNA Plasmid (h) - sc-96557-SH from Santa Cruz Biotechnology
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MMP-27 shRNA (h) Lentiviral Particles - sc-96557-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN14436 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14436 from Sigma-Aldrich
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MMP27 siRNA (Human) - CRJ1899 from Cohesion Biosciences
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shRNA set against Human MMP27 (NM_022122.2) - SHH343072 from Creative biogene
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shRNA set against Human MMP27(NM_022122.2) - SHH193997 from Creative biogene
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Human MMP27 siRNA - orb272400 from Biorbyt
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MMP27 shRNA Plasmid (Human) - CHJ1899 from Cohesion Biosciences
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MMP27 miRNA 3'UTR clone - MiUTR1H-06358 from Creative biogene
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