Gene Symbol | GBP4 |
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Entrez Gene | 115361 |
Alt Symbol | Mpa2 |
Species | Human |
Gene Type | protein-coding |
Description | guanylate binding protein 4 |
Other Description | GBP-4|GTP-binding protein 4|guanine nucleotide-binding protein 4|guanylate-binding protein 4 |
Swissprots | Q6NSL0 Q86T99 Q96PP9 Q05D63 B2R630 |
Accessions | EAW73142 EAW73143 EAW73144 Q96PP9 AF288814 AAL02054 AK131094 BAC85144 AK304245 BAG65113 AK312417 BAG35327 AL832576 CAD89936 BC008421 BC017889 AAH17889 BC050625 BC070055 AAH70055 CA309701 NM_052941 NP_443173 |
Function | Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17266443}. Nucleus {ECO:0000269|PubMed:17266443}. |
GBP4 CRISPR/Cas9 KO Plasmid (h) - sc-405870 from Santa Cruz Biotechnology
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GBP4 HDR Plasmid (h) - sc-405870-HDR from Santa Cruz Biotechnology
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GBP4 Double Nickase Plasmid (h) - sc-405870-NIC from Santa Cruz Biotechnology
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GBP4 Double Nickase Plasmid (h2) - sc-405870-NIC-2 from Santa Cruz Biotechnology
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GBP4 CRISPR Activation Plasmid (h) - sc-405870-ACT from Santa Cruz Biotechnology
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GBP4 CRISPR Activation Plasmid (h2) - sc-405870-ACT-2 from Santa Cruz Biotechnology
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GBP4 Lentiviral Activation Particles (h) - sc-405870-LAC from Santa Cruz Biotechnology
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GBP4 Lentiviral Activation Particles (h2) - sc-405870-LAC-2 from Santa Cruz Biotechnology
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GBP4 siRNA (h) - sc-88062 from Santa Cruz Biotechnology
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GBP4 shRNA Plasmid (h) - sc-88062-SH from Santa Cruz Biotechnology
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GBP4 shRNA (h) Lentiviral Particles - sc-88062-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU015611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9171 from Sigma-Aldrich
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GBP4 siRNA (Human) - CRJ4445 from Cohesion Biosciences
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GBP4 - MBS8240193 from MyBioSource
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GBP4 CRISPR/Cas9 KO Plasmid (h2) - sc-405870-KO-2 from Santa Cruz Biotechnology
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GBP4 HDR Plasmid (h2) - sc-405870-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GBP4 (NM_052941.4) - SHH299818 from Creative biogene
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Human GBP4 siRNA - orb274946 from Biorbyt
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GBP4 shRNA Plasmid (Human) - CHJ4445 from Cohesion Biosciences
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GBP4 miRNA 3'UTR clone - MiUTR4H-TG11288 from Creative biogene
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