Gene Symbol | RTN4RL2 |
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Entrez Gene | 349667 |
Alt Symbol | NGRH1, NgR2 |
Species | Human |
Gene Type | protein-coding |
Description | reticulon 4 receptor-like 2 |
Other Description | Nogo-66 receptor homolog 1|nogo receptor-like 3|nogo-66 receptor-related protein 2|reticulon-4 receptor-like 2 |
Swissprots | Q17RL9 Q86UN3 Q6X813 Q0GGW3 |
Accessions | EAW73747 EAW73748 Q86UN3 AF532858 AAP21835 AX751514 CAD99155 AY250221 AAP82838 BC113673 AAI13674 BC117276 AAI17277 BC143818 AAI43819 BE410139 BK001302 DAA01385 BU845536 DQ864979 ABI23432 HY323308 NM_178570 NP_848665 |
Function | May play a role in regulating axonal regeneration and plasticity in the adult central nervous system. {ECO:0000303|PubMed:14664809}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12694398}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:12694398}. Note=Localized to the surface of neurons, including axons. |
Tissue Specificity | Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid. {ECO:0000269|PubMed:12694398, ECO:0000269|PubMed:14664809}. |
NgR2 CRISPR/Cas9 KO Plasmid (h) - sc-408362 from Santa Cruz Biotechnology
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NgR2 HDR Plasmid (h) - sc-408362-HDR from Santa Cruz Biotechnology
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NgR2 Double Nickase Plasmid (h) - sc-408362-NIC from Santa Cruz Biotechnology
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NgR2 Double Nickase Plasmid (h2) - sc-408362-NIC-2 from Santa Cruz Biotechnology
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NgR2 CRISPR Activation Plasmid (h) - sc-408362-ACT from Santa Cruz Biotechnology
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NgR2 CRISPR Activation Plasmid (h2) - sc-408362-ACT-2 from Santa Cruz Biotechnology
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NgR2 Lentiviral Activation Particles (h) - sc-408362-LAC from Santa Cruz Biotechnology
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NgR2 Lentiviral Activation Particles (h2) - sc-408362-LAC-2 from Santa Cruz Biotechnology
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NgR2 siRNA (h) - sc-96573 from Santa Cruz Biotechnology
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NgR2 shRNA Plasmid (h) - sc-96573-SH from Santa Cruz Biotechnology
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NgR2 shRNA (h) Lentiviral Particles - sc-96573-V from Santa Cruz Biotechnology
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NgR2/NgRH1/RTN4RL2 RNAi - H00349667-R02 from Novus Biologicals
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MISSION® esiRNA - EHU138991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18741 from Sigma-Aldrich
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RTN4RL2 siRNA (Human) - CRJ7553 from Cohesion Biosciences
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RTN4RL2 - MBS8235521 from MyBioSource
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shRNA set against Human RTN4RL2 (NM_178570.1) - SHH400592 from Creative biogene
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shRNA set against Human RTN4RL2(NM_178570.1) - SHR201264 from Creative biogene
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Human RTN4RL2 siRNA - orb278054 from Biorbyt
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RTN4RL2 shRNA Plasmid (Human) - CHJ7553 from Cohesion Biosciences
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RTN4RL2 miRNA 3'UTR clone - MiUTR1H-09073 from Creative biogene
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