Gene Symbol | DFFA |
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Entrez Gene | 1676 |
Alt Symbol | DFF-45, DFF1, ICAD |
Species | Human |
Gene Type | protein-coding |
Description | DNA fragmentation factor, 45kDa, alpha polypeptide |
Other Description | DFF45|DNA fragmentation factor 45 kDa subunit|DNA fragmentation factor subunit alpha|inhibitor of CAD |
Swissprots | Q96I97 Q5T6G5 Q9Y6C6 Q5T6G6 O00273 |
Accessions | EAW71655 EAW71656 EAW71657 EAW71658 O00273 AF087573 AAD32953 AF103799 AAF02419 AK222546 BAD96266 AK313317 BAG36122 AU121791 BC000037 AAH00037 BC007112 AAH07112 BC007721 AAH07721 BE207821 BT006980 AAP35626 BU956486 U91985 AAC51249 NM_004401 NP_004392 NM_213566 NP_998731 |
Function | Inhibitor of the caspase-activated DNase (DFF40). |
Subcellular Location | Cytoplasm. |
Top Pathways | Apoptosis |
ICAD CRISPR/Cas9 KO Plasmid (h) - sc-403560 from Santa Cruz Biotechnology
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ICAD HDR Plasmid (h) - sc-403560-HDR from Santa Cruz Biotechnology
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ICAD Double Nickase Plasmid (h) - sc-403560-NIC from Santa Cruz Biotechnology
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ICAD Double Nickase Plasmid (h2) - sc-403560-NIC-2 from Santa Cruz Biotechnology
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ICAD CRISPR Activation Plasmid (h) - sc-403560-ACT from Santa Cruz Biotechnology
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ICAD CRISPR Activation Plasmid (h2) - sc-403560-ACT-2 from Santa Cruz Biotechnology
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ICAD Lentiviral Activation Particles (h) - sc-403560-LAC from Santa Cruz Biotechnology
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ICAD Lentiviral Activation Particles (h2) - sc-403560-LAC-2 from Santa Cruz Biotechnology
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ICAD siRNA (h) - sc-35624 from Santa Cruz Biotechnology
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ICAD shRNA Plasmid (h) - sc-35624-SH from Santa Cruz Biotechnology
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ICAD shRNA (h) Lentiviral Particles - sc-35624-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU080301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7161 from Sigma-Aldrich
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DFFA siRNA (Human) - CRH1185 from Cohesion Biosciences
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DFFA - MBS8206541 from MyBioSource
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shRNA set against Human DFFA (NM_004401.2) - SHH277277 from Creative biogene
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shRNA set against Human DFFA(NM_004401.2) - SHH002143 from Creative biogene
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shRNA set against Human DFFA(NM_213566.1) - SHH002189 from Creative biogene
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Human DFFA siRNA - orb261687 from Biorbyt
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DFFA shRNA Plasmid (Human) - CHH1185 from Cohesion Biosciences
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DFFA miRNA 3'UTR clone - MiUTR1H-02787 from Creative biogene
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DFFA miRNA 3'UTR clone - MiUTR1H-02788 from Creative biogene
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