Gene Symbol | SLC6A12 |
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Entrez Gene | 6539 |
Alt Symbol | BGT-1, BGT1, GAT2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 6 (neurotransmitter transporter), member 12 |
Other Description | Na(+)/Cl(-) betaine/GABA transporter|betaine/GABA transporter-1|gamma-aminobutyric acid transporter|sodium- and chloride-dependent betaine transporter|solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 |
Swissprots | P48065 A0AV52 D3DUN8 B2R992 |
Accessions | EAW88975 EAW88976 EAW88977 EAW88978 P48065 AI241640 AK096046 BAG53203 AK125026 BAG54125 AK131564 BAD18697 AK307167 AK313690 BAG36439 BC026339 BC036838 BC126215 AAI26216 BC126217 AAI26218 DA093632 DA390883 DA406088 DA638367 HQ258313 ADR83067 L42300 AAA66574 U27699 AAA87029 XM_005253746 XP_005253803 XM_005253747 XP_005253804 XM_005253748 XP_005253805 XM_006719005 XP_006719068 XM_011521010 XP_011519312 XM_011521011 XP_011519313 NM_001122847 NP_001116319 NM_001122848 NP_001116320 NM_001206931 NP_001193860 NM_003044 NP_003035 |
Function | Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain. |
BGT-1 CRISPR/Cas9 KO Plasmid (h) - sc-417225 from Santa Cruz Biotechnology
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BGT-1 HDR Plasmid (h) - sc-417225-HDR from Santa Cruz Biotechnology
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BGT-1 Double Nickase Plasmid (h) - sc-417225-NIC from Santa Cruz Biotechnology
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BGT-1 Double Nickase Plasmid (h2) - sc-417225-NIC-2 from Santa Cruz Biotechnology
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BGT-1 CRISPR Activation Plasmid (h) - sc-417225-ACT from Santa Cruz Biotechnology
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BGT-1 CRISPR Activation Plasmid (h2) - sc-417225-ACT-2 from Santa Cruz Biotechnology
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BGT-1 Lentiviral Activation Particles (h) - sc-417225-LAC from Santa Cruz Biotechnology
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BGT-1 Lentiviral Activation Particles (h2) - sc-417225-LAC-2 from Santa Cruz Biotechnology
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BGT-1 siRNA (h) - sc-95904 from Santa Cruz Biotechnology
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BGT-1 shRNA Plasmid (h) - sc-95904-SH from Santa Cruz Biotechnology
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BGT-1 shRNA (h) Lentiviral Particles - sc-95904-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU085891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19673 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19673 from Sigma-Aldrich
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SLC6A12 siRNA (Human) - CRH4432 from Cohesion Biosciences
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SLC6A12 RNAi - H00006539-R01 from Novus Biologicals
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SLC6A12 - MBS8234448 from MyBioSource
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shRNA set against Human SLC6A12 (NM_003044.4) - SHH411824 from Creative biogene
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Human SLC6A12 siRNA - orb264934 from Biorbyt
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SLC6A12 shRNA Plasmid (Human) - CHH4432 from Cohesion Biosciences
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SLC6A12 miRNA 3'UTR clone - MiUTR3H-05646 from Creative biogene
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SLC6A12 miRNA 3'UTR clone - MiUTR3H-05647 from Creative biogene
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SLC6A12 miRNA 3'UTR clone - MiUTR3H-05648 from Creative biogene
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