Gene Symbol |
BRINP1
|
Entrez Gene |
1620
|
Alt Symbol |
DBC1, DBCCR1, FAM5A
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
bone morphogenetic protein/retinoic acid inducible neural-specific 1
|
Other Description |
BMP/retinoic acid-inducible neural-specific protein 1|bA574M5.1 (deleted in bladder cancer chromosome region candidate 1 (IB3089A))|bone morphogenic protein/retinoic acid inducible neural-specific 1|deleted in bladder cancer 1|deleted in bladder cancer chromosome region candidate 1|deleted in bladder cancer protein 1
|
Swissprots |
Q8WU22 O60477 Q6P1A0 Q6IPV6
|
Accessions |
EAW87455 EAW87456 O60477 AF027734 AAC39691 AK293501 BAG56986 AK293649 BAG57101 BC021560 AAH21560 BC065196 AAH65196 BC071702 AAH71702 Z41452 NM_014618 NP_055433
|
Function |
Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway. {ECO:0000269|PubMed:11420708, ECO:0000269|PubMed:14712213, ECO:0000269|PubMed:16369496}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11420708}.
|
Tissue Specificity |
Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine. {ECO:0000269|PubMed:9545632}.
|