Gene Symbol |
SERTAD1
|
Entrez Gene |
29950
|
Alt Symbol |
SEI1, TRIP-Br1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
SERTA domain containing 1
|
Other Description |
CDK4-binding protein p34SEI|CDK4-binding protein p34SEI1|SEI-1|SERTA domain-containing protein 1|transcriptional regulator interacting with the PHD-bromodomain 1
|
Swissprots |
Q9BUE7 Q9UHV2
|
Accessions |
AAM77800 CAF86711 CAI93561 EAW56964 EAW56965 Q9UHV2 AA928491 AF117959 AAF08349 AF366402 AAK52831 AK074652 BAG51982 AK222970 BAD96690 AK223011 BAD96731 BC002670 AAH02670 DQ892993 ABM83919 DQ896241 ABM87240 NM_013376 NP_037508
|
Function |
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
|