Gene Symbol | COX7B |
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Entrez Gene | 1349 |
Alt Symbol | APLCC |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome c oxidase subunit VIIb |
Other Description | cytochrome c oxidase polypeptide VIIb|cytochrome c oxidase subunit 7B, mitochondrial|cytochrome-c oxidase chain VIIb |
Swissprots | Q6ICR1 P24311 B2R4M3 |
Accessions | EAW98607 P24311 AK311879 BAG34820 BC018386 AAH18386 BT009767 AAP88769 CR450332 CAG29328 CR542124 CAG46921 DQ890544 ABM92161 EU176472 ABW03273 Z14244 CAA78613 NM_001866 NP_001857 |
Function | This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Plays a role in proper central nervous system (CNS) development in vertebrates. {ECO:0000269|PubMed:23122588}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000250}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
COX7b CRISPR/Cas9 KO Plasmid (h) - sc-417254 from Santa Cruz Biotechnology
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COX7b HDR Plasmid (h) - sc-417254-HDR from Santa Cruz Biotechnology
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COX7b Double Nickase Plasmid (h) - sc-417254-NIC from Santa Cruz Biotechnology
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COX7b Double Nickase Plasmid (h2) - sc-417254-NIC-2 from Santa Cruz Biotechnology
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COX7b CRISPR Activation Plasmid (h) - sc-417254-ACT from Santa Cruz Biotechnology
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COX7b CRISPR Activation Plasmid (h2) - sc-417254-ACT-2 from Santa Cruz Biotechnology
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COX7b Lentiviral Activation Particles (h) - sc-417254-LAC from Santa Cruz Biotechnology
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COX7b Lentiviral Activation Particles (h2) - sc-417254-LAC-2 from Santa Cruz Biotechnology
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COX7b siRNA (h) - sc-91062 from Santa Cruz Biotechnology
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COX7b shRNA Plasmid (h) - sc-91062-SH from Santa Cruz Biotechnology
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COX7b shRNA (h) Lentiviral Particles - sc-91062-V from Santa Cruz Biotechnology
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COX7B RNAi - H00001349-R01 from Novus Biologicals
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MISSION® esiRNA - EHU112071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6482 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6482 from Sigma-Aldrich
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COX7B siRNA (Human) - CRH0940 from Cohesion Biosciences
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COX7B - MBS8232180 from MyBioSource
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shRNA set against Human COX7B (NM_001866.2) - SHH268401 from Creative biogene
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shRNA set against Human COX7B(NM_001866.2) - SHG194983 from Creative biogene
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Human COX7B siRNA - orb261442 from Biorbyt
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COX7B shRNA Plasmid (Human) - CHH0940 from Cohesion Biosciences
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COX7B miRNA 3'UTR clone - MiUTR1H-02379 from Creative biogene
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