Gene Symbol | CLPS |
---|---|
Entrez Gene | 1208 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | colipase, pancreatic |
Other Description | colipase|pancreatic colipase preproprotein |
Swissprots | Q5U809 Q5T9G7 P04118 |
Accessions | AAB05818 EAX03850 EAX03851 P04118 AY780648 AAV35728 AY780649 AAV35729 BC007061 AAH07061 BC017897 AAH17897 BC025693 BC043489 BI439786 BP321569 BP322637 BP324927 BQ271978 BT006812 AAP35458 J02883 AAA52054 JF432763 ADZ15980 NM_001252597 NP_001239526 NM_001252598 NP_001239527 NM_001832 NP_001823 |
Function | Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the pancreas. |
Top Pathways | Fat digestion and absorption |