| Gene Symbol |
COL16A1
|
| Entrez Gene |
1307
|
| Alt Symbol |
447AA, FP1572
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
collagen, type XVI, alpha 1
|
| Other Description |
alpha 1 type XVI collagen|collagen XVI, alpha-1 polypeptide|collagen alpha-1(XVI) chain
|
| Swissprots |
Q07092 Q16593 Q59F89 Q71RG9
|
| Accessions |
EAX07595 EAX07596 EAX07597 Q07092 AB209571 BAD92808 AF370368 AAQ15204 BC064839 BC167814 AAI67814 M92642 AAA58427 R54778 S57132 AAB25797 X14963 CAA33085 X15038 CAA33142 XM_005270481 XP_005270538 XM_011540722 XP_011539024 XM_011540723 XP_011539025 XM_011540724 XP_011539026 XM_011540725 XP_011539027 XM_011540726 XP_011539028 XM_011540727 XP_011539029 XM_011540728 XP_011539030 XM_011540729 XP_011539031 XM_011540730 XP_011539032 XR_946546 NM_001856 NP_001847
|
| Function |
Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology. {ECO:0000269|PubMed:16754661}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:9022684}.
|
| Tissue Specificity |
In papillary dermis, is a component of specialized fibrillin-1-containing microfibrils, whereas in territorial cartilage matrix, it is localized to a discrete population of thin, weakly banded collagen fibrils in association with other collagens (at protein level). In the placenta, where it is found in the amnion, a membranous tissue lining the amniotic cavity. Within the amnion, it is found in an acellular, relatively dense layer of a complex network of reticular fibers. Also located to a fibroblast layer beneath this dense layer. Exists in tissues in association with other types of collagen. {ECO:0000269|PubMed:12782140}.
|