LTBP1
| Gene Symbol | LTBP1 |
|---|---|
| Entrez Gene | 4052 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | latent transforming growth factor beta binding protein 1 |
| Other Description | LTBP-1|TGF-beta1-BP-1|latent-transforming growth factor beta-binding protein 1|transforming growth factor beta-1-binding protein 1 |
| Swissprots | Q53SG1 Q53SD8 Q14766 Q8TD95 A1L3V1 Q59HF7 P22064 Q53SF3 |
| Accessions | AAA96327 AAF08252 AAF08253 AAY14953 AAY15036 AAY24260 EAX00435 EAX00436 EAX00437 EAX00438 EAX00439 Q14766 AA935267 AB208801 BAD92038 AF489528 AAM03124 AK298027 BAG60329 AK299237 BAG61269 AK299912 BAG61750 AK302857 BAG64043 AK315991 BAH14362 AL703596 BC130289 AAI30290 BC144127 BC144128 AAI44129 BM147075 BX103725 BX472809 BX492839 CA419949 CD657511 CF995689 DR001861 M34057 AAA61160 XM_005264317 XP_005264374 XM_005264318 XP_005264375 XM_011532853 XP_011531155 XM_011532854 XP_011531156 XM_011532855 XP_011531157 XM_011532856 XP_011531158 XM_011532857 XP_011531159 XM_011532858 XP_011531160 XM_011532859 XP_011531161 XM_011532860 XP_011531162 XM_011532861 XP_011531163 XM_011532862 XP_011531164 NM_000627 NP_000618 NM_001166264 NP_001159736 NM_001166265 NP_001159737 NM_001166266 NP_001159738 NM_206943 NP_996826 |
| Function | May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). |
| Subcellular Location | Secreted. |
| Tissue Specificity | Isoform Long is found in fibroblasts. |
| Top Pathways | TGF-beta signaling pathway |
LTBP-1 CRISPR/Cas9 KO Plasmid (h) - sc-402289 from Santa Cruz Biotechnology
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LTBP-1 HDR Plasmid (h) - sc-402289-HDR from Santa Cruz Biotechnology
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LTBP-1 Double Nickase Plasmid (h) - sc-402289-NIC from Santa Cruz Biotechnology
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LTBP-1 Double Nickase Plasmid (h2) - sc-402289-NIC-2 from Santa Cruz Biotechnology
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LTBP-1 CRISPR Activation Plasmid (h) - sc-402289-ACT from Santa Cruz Biotechnology
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LTBP-1 CRISPR Activation Plasmid (h2) - sc-402289-ACT-2 from Santa Cruz Biotechnology
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LTBP-1 Lentiviral Activation Particles (h) - sc-402289-LAC from Santa Cruz Biotechnology
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LTBP-1 Lentiviral Activation Particles (h2) - sc-402289-LAC-2 from Santa Cruz Biotechnology
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LTBP-1 siRNA (h) - sc-45454 from Santa Cruz Biotechnology
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LTBP-1 shRNA Plasmid (h) - sc-45454-SH from Santa Cruz Biotechnology
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LTBP-1 shRNA (h) Lentiviral Particles - sc-45454-V from Santa Cruz Biotechnology
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Latent TGF-beta bp1 RNAi - H00004052-R05 from Novus Biologicals
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MISSION® esiRNA - EHU077411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12815 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12815 from Sigma-Aldrich
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LTBP1 siRNA (Human) - CRH2741 from Cohesion Biosciences
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Latent TGF-beta bp1 RNAi - H00004052-R06 from Novus Biologicals
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LTBP-1 CRISPR/Cas9 KO Plasmid (h2) - sc-402289-KO-2 from Santa Cruz Biotechnology
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LTBP-1 HDR Plasmid (h2) - sc-402289-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human Ltbp1 (NM_000627.3) - SHH335463 from Creative biogene
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Human LTBP1 siRNA - orb263243 from Biorbyt
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LTBP1 shRNA Plasmid (Human) - CHH2741 from Cohesion Biosciences
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LTBP1 miRNA 3'UTR clone - MiUTR3H-01294 from Creative biogene
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LTBP1 miRNA 3'UTR clone - MiUTR3H-01295 from Creative biogene
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LTBP1 miRNA 3'UTR clone - MiUTR3H-01296 from Creative biogene
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