Gene Symbol | KCNJ9 |
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Entrez Gene | 3765 |
Alt Symbol | GIRK3, KIR3.3 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, inwardly rectifying subfamily J, member 9 |
Other Description | G protein-activated inward rectifier potassium channel 3|G protein-coupled inward rectifier potassium channel|GIRK-3|inward rectifier K(+) channel Kir3.3|inwardly rectifier K+ channel KIR3.3|potassium channel, inwardly rectifying subfamily J member 9|potassium inwardly-rectifying channel, subfamily J, member 9 |
Swissprots | Q5JW75 Q92806 |
Accessions | AAF89098 EAW52747 Q92806 BC117516 BC117517 BC117518 BC117519 BC167777 AAI67777 U52152 AAB07043 XM_006711305 XP_006711368 XM_011509515 XP_011507817 XM_011509516 XP_011507818 XM_011509517 XP_011507819 XM_011509518 XP_011507820 XM_011509519 XP_011507821 XM_011509520 XP_011507822 NM_004983 NP_004974 |
Function | This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | Dopaminergic synapse, Morphine addiction, Retrograde endocannabinoid signaling, Circadian entrainment, Estrogen signaling pathway |
KIR3.3 CRISPR/Cas9 KO Plasmid (h) - sc-410847 from Santa Cruz Biotechnology
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KIR3.3 HDR Plasmid (h) - sc-410847-HDR from Santa Cruz Biotechnology
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KIR3.3 Double Nickase Plasmid (h) - sc-410847-NIC from Santa Cruz Biotechnology
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KIR3.3 Double Nickase Plasmid (h2) - sc-410847-NIC-2 from Santa Cruz Biotechnology
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KIR3.3 CRISPR Activation Plasmid (h) - sc-410847-ACT from Santa Cruz Biotechnology
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KIR3.3 CRISPR Activation Plasmid (h2) - sc-410847-ACT-2 from Santa Cruz Biotechnology
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KIR3.3 Lentiviral Activation Particles (h) - sc-410847-LAC from Santa Cruz Biotechnology
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KIR3.3 Lentiviral Activation Particles (h2) - sc-410847-LAC-2 from Santa Cruz Biotechnology
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KIR3.3 siRNA (h) - sc-42620 from Santa Cruz Biotechnology
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KIR3.3 shRNA Plasmid (h) - sc-42620-SH from Santa Cruz Biotechnology
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KIR3.3 shRNA (h) Lentiviral Particles - sc-42620-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU121131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10961 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09841 from Sigma-Aldrich
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KCNJ9 siRNA (Human) - CRH2541 from Cohesion Biosciences
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Kir3.3 RNAi - H00003765-R01 from Novus Biologicals
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shRNA set against Human Kcnj9 (NM_004983.2) - SHH323347 from Creative biogene
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shRNA set against Human KCNJ9(NM_004983.2) - SHL191262 from Creative biogene
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Human KCNJ9 siRNA - orb263043 from Biorbyt
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KCNJ9 shRNA Plasmid (Human) - CHH2541 from Cohesion Biosciences
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KCNJ9 miRNA 3'UTR clone - MiUTR1H-05140 from Creative biogene
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