| Gene Symbol |
DENND3
|
| Entrez Gene |
22898
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DENN/MADD domain containing 3
|
| Other Description |
DENN domain-containing protein 3
|
| Swissprots |
Q96DK3 B7ZM28 Q2TAM7 Q6ZMS6 O94947 A2RUS2
|
| Accessions |
A2RUS2 CCQ43475 EAW92216 EAW92217 EAW92218 EAW92219 EAW92220 AB020677 BAA74893 AK057136 AK058001 BAB71630 AK091556 BAG52379 AK123283 AK125506 AK131505 BAD18649 AL110264 AL544320 AW500126 BC110827 BC133023 AAI33024 BC144226 AAI44227 BF898211 CB989310 XM_005250838 XP_005250895 XM_005250839 XP_005250896 XM_005250840 XP_005250897 XM_005250841 XP_005250898 XM_005250842 XP_005250899 XM_005250843 XP_005250900 XM_011516933 XP_011515235 XM_011516934 XP_011515236 XM_011516935 XP_011515237 XM_011516936 XP_011515238 XM_011516937 XP_011515239 XM_011516938 XP_011515240 XM_011516939 XP_011515241 XM_011516940 XP_011515242 XM_011516941 XP_011515243 XM_011516942 XP_011515244 XR_242384 XR_928310 XR_928311 XR_928312 NM_014957 NP_055772
|
| Function |
Guanine nucleotide exchange factor (GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. {ECO:0000269|PubMed:20937701}.
|
![Western Blot: DENND3 Overexpression Lysate (Adult Normal) [NBL1-09830] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DENND3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8798_DENND3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09830-img0002.jpg)