Gene Symbol | FGD6 |
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Entrez Gene | 55785 |
Alt Symbol | ZFYVE24 |
Species | Human |
Gene Type | protein-coding |
Description | FYVE, RhoGEF and PH domain containing 6 |
Other Description | FYVE, RhoGEF and PH domain-containing protein 6|zinc finger FYVE domain-containing protein 24 |
Swissprots | Q96D44 Q6ZR53 Q9P2I5 Q9NUR8 Q7Z2Z7 Q6ZV73 |
Accessions | EAW97521 Q6ZV73 AB037783 BAA92600 AK002045 BAA92052 AK026881 AK124904 BAC85990 AK128492 BAC87464 BC013319 AAH13319 BC125225 AAI25226 BC125226 AAI25227 BC167803 AAI67803 BX538322 CAD98096 NM_018351 NP_060821 |
Function | May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000305}. |
FGD6 CRISPR/Cas9 KO Plasmid (h) - sc-412606 from Santa Cruz Biotechnology
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FGD6 HDR Plasmid (h) - sc-412606-HDR from Santa Cruz Biotechnology
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FGD6 Double Nickase Plasmid (h) - sc-412606-NIC from Santa Cruz Biotechnology
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FGD6 Double Nickase Plasmid (h2) - sc-412606-NIC-2 from Santa Cruz Biotechnology
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FGD6 CRISPR Activation Plasmid (h) - sc-412606-ACT from Santa Cruz Biotechnology
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FGD6 CRISPR Activation Plasmid (h2) - sc-412606-ACT-2 from Santa Cruz Biotechnology
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FGD6 Lentiviral Activation Particles (h) - sc-412606-LAC from Santa Cruz Biotechnology
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FGD6 Lentiviral Activation Particles (h2) - sc-412606-LAC-2 from Santa Cruz Biotechnology
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FGD6 siRNA (h) - sc-95963 from Santa Cruz Biotechnology
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FGD6 shRNA Plasmid (h) - sc-95963-SH from Santa Cruz Biotechnology
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FGD6 shRNA (h) Lentiviral Particles - sc-95963-V from Santa Cruz Biotechnology
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FGD6 RNAi - H00055785-R01 from Novus Biologicals
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MISSION® esiRNA - EHU076451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8644 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8644 from Sigma-Aldrich
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FGD6 siRNA (Human) - CRJ0919 from Cohesion Biosciences
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FGD6 - MBS8216803 from MyBioSource
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shRNA set against Human FGD6 (NM_018351.3) - SHH294349 from Creative biogene
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shRNA set against Human FGD6(NM_018351.3) - SHH056693 from Creative biogene
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Human FGD6 siRNA - orb271420 from Biorbyt
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FGD6 shRNA Plasmid (Human) - CHJ0919 from Cohesion Biosciences
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FGD6 miRNA 3'UTR clone - MiUTR1H-03623 from Creative biogene
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