Gene Symbol | COQ7 |
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Entrez Gene | 10229 |
Alt Symbol | CAT5, CLK-1, CLK1 |
Species | Human |
Gene Type | protein-coding |
Description | coenzyme Q7 homolog, ubiquinone (yeast) |
Other Description | COQ7 coenzyme Q, 7 homolog ubiquinone|coenzyme Q biosynthesis protein 7 homolog|placental protein KG-20|timing protein clk-1 homolog|ubiquinone biosynthesis protein COQ7 homolog |
Swissprots | Q9UNR5 Q9UEW5 Q9H0T5 Q99807 Q9BTT7 B2RDA9 |
Accessions | AAD43650 EAW50268 EAW50269 EAW50270 EAW50271 Q99807 AF032900 AAC69451 AF098948 AAD43648 AF374413 AAM21346 AI279093 AI424412 AK024291 BAB14876 AK225115 AK315470 BAG37856 AL136647 CAB66582 AM393051 CAL37929 AM393521 CAL38398 BC003185 AAH03185 BC043272 AAH43272 U81276 AAC51120 XR_950722 NM_001190983 NP_001177912 NM_016138 NP_057222 |
Function | Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=Synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. {ECO:0000250}. |
Tissue Specificity | Expressed dominantly in heart and skeletal muscle. |
Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis |
COQ7 CRISPR/Cas9 KO Plasmid (h) - sc-405183 from Santa Cruz Biotechnology
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COQ7 HDR Plasmid (h) - sc-405183-HDR from Santa Cruz Biotechnology
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COQ7 Double Nickase Plasmid (h) - sc-405183-NIC from Santa Cruz Biotechnology
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COQ7 Double Nickase Plasmid (h2) - sc-405183-NIC-2 from Santa Cruz Biotechnology
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COQ7 CRISPR Activation Plasmid (h) - sc-405183-ACT from Santa Cruz Biotechnology
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COQ7 CRISPR Activation Plasmid (h2) - sc-405183-ACT-2 from Santa Cruz Biotechnology
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COQ7 Lentiviral Activation Particles (h) - sc-405183-LAC from Santa Cruz Biotechnology
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COQ7 Lentiviral Activation Particles (h2) - sc-405183-LAC-2 from Santa Cruz Biotechnology
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COQ7 siRNA (h) - sc-62146 from Santa Cruz Biotechnology
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COQ7 shRNA Plasmid (h) - sc-62146-SH from Santa Cruz Biotechnology
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COQ7 shRNA (h) Lentiviral Particles - sc-62146-V from Santa Cruz Biotechnology
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CLK1 RNAi - H00001195-R04 from Novus Biologicals
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MISSION® esiRNA - EHU006301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6449 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6449 from Sigma-Aldrich
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COQ7 siRNA (Human) - CRH6917 from Cohesion Biosciences
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COQ7 - MBS8210599 from MyBioSource
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shRNA set against Human COQ7 (NM_016138.4) - SHH268009 from Creative biogene
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COQ7 shRNA Plasmid (Human) - CHH6917 from Cohesion Biosciences
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COQ7 miRNA 3'UTR clone - MiUTR3H-04318 from Creative biogene
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