Gene Symbol | GPT2 |
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Entrez Gene | 84706 |
Alt Symbol | ALT2, GPT 2, MRT49 |
Species | Human |
Gene Type | protein-coding |
Description | glutamic pyruvate transaminase (alanine aminotransferase) 2 |
Other Description | alanine aminotransferase 2|glutamate pyruvate transaminase 2|glutamic--alanine transaminase 2|glutamic--pyruvic transaminase 2 |
Swissprots | Q8TD30 Q8N9E2 |
Accessions | EAW82690 EAW82691 EAW82692 Q8TD30 AI990701 AK090957 BAG52252 AK094971 BAC04465 AL833351 AY029173 AAK31794 BC051364 BC062555 AAH62555 BE466380 DA400677 HY117879 NM_001142466 NP_001135938 NM_133443 NP_597700 |
Function | Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. {ECO:0000269|PubMed:11863375}. |
Tissue Specificity | Expressed at high levels in muscle, adipose tissue, kidney and brain and at lower levels in the liver and breast. {ECO:0000269|PubMed:11863375}. |
Top Pathways | Alanine, aspartate and glutamate metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Carbon metabolism |
GPT2 CRISPR/Cas9 KO Plasmid (h) - sc-403739 from Santa Cruz Biotechnology
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GPT2 HDR Plasmid (h) - sc-403739-HDR from Santa Cruz Biotechnology
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GPT2 Double Nickase Plasmid (h) - sc-403739-NIC from Santa Cruz Biotechnology
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GPT2 Double Nickase Plasmid (h2) - sc-403739-NIC-2 from Santa Cruz Biotechnology
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GPT2 CRISPR Activation Plasmid (h) - sc-403739-ACT from Santa Cruz Biotechnology
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GPT2 CRISPR Activation Plasmid (h2) - sc-403739-ACT-2 from Santa Cruz Biotechnology
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GPT2 Lentiviral Activation Particles (h) - sc-403739-LAC from Santa Cruz Biotechnology
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GPT2 Lentiviral Activation Particles (h2) - sc-403739-LAC-2 from Santa Cruz Biotechnology
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GPT2 siRNA (h) - sc-45647 from Santa Cruz Biotechnology
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GPT2 shRNA Plasmid (h) - sc-45647-SH from Santa Cruz Biotechnology
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GPT2 shRNA (h) Lentiviral Particles - sc-45647-V from Santa Cruz Biotechnology
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GPT2 RNAi - H00084706-R01 from Novus Biologicals
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MISSION® esiRNA - EHU041201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9644 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9644 from Sigma-Aldrich
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GPT2 siRNA (Human) - CRJ3595 from Cohesion Biosciences
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GPT2 - MBS8230785 from MyBioSource
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shRNA set against Human GPT2 (NM_133443.2) - SHH307350 from Creative biogene
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Human GPT2 siRNA - orb274096 from Biorbyt
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GPT2 shRNA Plasmid (Human) - CHJ3595 from Cohesion Biosciences
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