Gene Symbol | MPHOSPH10 |
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Entrez Gene | 10199 |
Alt Symbol | CT90, MPP10, MPP10P, PPP1R106 |
Species | Human |
Gene Type | protein-coding |
Description | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
Other Description | U3 small nucleolar ribonucleoprotein protein MPP10|m phase phosphoprotein 10|protein phosphatase 1, regulatory subunit 106 |
Swissprots | A0AVJ8 O00566 |
Accessions | EAW99776 EAW99777 O00566 AI056034 AK056862 BAG51817 AK310931 BC015158 BC041084 BC126389 AAI26390 DA867290 X98494 CAA67120 NM_005791 NP_005782 |
Function | Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. |
Subcellular Location | Nucleus, nucleolus. Chromosome. Note=Fibrillar region of the nucleolus. After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase. In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin. The reassociation with nucleolus is preceeded by the arrival of fibrillarin. |
Top Pathways | Ribosome biogenesis in eukaryotes |
MPP10 CRISPR/Cas9 KO Plasmid (h) - sc-406199 from Santa Cruz Biotechnology
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MPP10 HDR Plasmid (h) - sc-406199-HDR from Santa Cruz Biotechnology
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MPP10 Double Nickase Plasmid (h) - sc-406199-NIC from Santa Cruz Biotechnology
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MPP10 Double Nickase Plasmid (h2) - sc-406199-NIC-2 from Santa Cruz Biotechnology
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MPP10 CRISPR Activation Plasmid (h) - sc-406199-ACT from Santa Cruz Biotechnology
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MPP10 CRISPR Activation Plasmid (h2) - sc-406199-ACT-2 from Santa Cruz Biotechnology
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MPP10 Lentiviral Activation Particles (h) - sc-406199-LAC from Santa Cruz Biotechnology
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MPP10 Lentiviral Activation Particles (h2) - sc-406199-LAC-2 from Santa Cruz Biotechnology
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MPP10 siRNA (h) - sc-94702 from Santa Cruz Biotechnology
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MPP10 shRNA Plasmid (h) - sc-94702-SH from Santa Cruz Biotechnology
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MPP10 shRNA (h) Lentiviral Particles - sc-94702-V from Santa Cruz Biotechnology
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MPHOSPH10 RNAi - H00010199-R01 from Novus Biologicals
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MISSION® esiRNA - EHU050741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14495 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14495 from Sigma-Aldrich
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MPHOSPH10 siRNA (Human) - CRH6888 from Cohesion Biosciences
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shRNA set against Human Mphosph10 (NM_005791.2) - SHH343828 from Creative biogene
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Human MPHOSPH10 siRNA - orb267390 from Biorbyt
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MPHOSPH10 shRNA Plasmid (Human) - CHH6888 from Cohesion Biosciences
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MPHOSPH10 miRNA 3'UTR clone - MiUTR3H-07741 from Creative biogene
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