Gene Symbol | C7 |
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Entrez Gene | 730 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | complement component 7 |
Other Description | complement component C7 |
Swissprots | Q6P3T5 P10643 Q92489 |
Accessions | CAA60121 EAW56007 EAW56008 P10643 AK290349 BAF83038 AK304848 BAG65588 AK312737 BAG35608 BC025402 AAH25402 BC041807 BC063851 AAH63851 BC065305 HQ258008 ADR82762 J03507 AAA51861 Y11720 CAA72407 XM_011514122 XP_011512424 NM_000587 NP_000578 |
Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases |
C7 CRISPR/Cas9 KO Plasmid (h) - sc-404773 from Santa Cruz Biotechnology
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C7 HDR Plasmid (h) - sc-404773-HDR from Santa Cruz Biotechnology
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C7 Double Nickase Plasmid (h) - sc-404773-NIC from Santa Cruz Biotechnology
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C7 Double Nickase Plasmid (h2) - sc-404773-NIC-2 from Santa Cruz Biotechnology
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C7 CRISPR Activation Plasmid (h) - sc-404773-ACT from Santa Cruz Biotechnology
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C7 CRISPR Activation Plasmid (h2) - sc-404773-ACT-2 from Santa Cruz Biotechnology
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C7 Lentiviral Activation Particles (h) - sc-404773-LAC from Santa Cruz Biotechnology
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C7 Lentiviral Activation Particles (h2) - sc-404773-LAC-2 from Santa Cruz Biotechnology
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C7 siRNA (h) - sc-91855 from Santa Cruz Biotechnology
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C7 shRNA Plasmid (h) - sc-91855-SH from Santa Cruz Biotechnology
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C7 shRNA (h) Lentiviral Particles - sc-91855-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU004001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5077 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5077 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09492 from Sigma-Aldrich
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C7 siRNA (Human) - CRH0507 from Cohesion Biosciences
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C7 - MBS8214651 from MyBioSource
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Human C7 siRNA - orb261009 from Biorbyt
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C7 shRNA Plasmid (Human) - CHH0507 from Cohesion Biosciences
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C7 miRNA 3'UTR clone - MiUTR1H-01480 from Creative biogene
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