| Gene Symbol |
COMMD4
|
| Entrez Gene |
54939
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
COMM domain containing 4
|
| Other Description |
COMM domain-containing protein 4
|
| Swissprots |
B2RBN4 Q9H0A8 Q7L637 Q9NX43 H3BUL2
|
| Accessions |
CAD34816 EAW99261 EAW99262 EAW99263 Q9H0A8 AK000459 BAA91178 AK057145 AK225716 AK293708 BAG57141 AK314740 BAG37281 AL136872 CAB66806 AW117823 AY542160 AAS22242 BC000837 AAH00837 BC033744 BC040944 BC068998 AAH68998 BC069195 BI829264 BI829484 BQ233598 BU540913 CR533452 CAG38483 DB524201 HY162014 XM_005254509 XP_005254566 XM_005254510 XP_005254567 XM_005254511 XP_005254568 XM_011521739 XP_011520041 XM_011521740 XP_011520042 XM_011521741 XP_011520043 NM_001284377 NP_001271306 NM_001284378 NP_001271307 NM_001284379 NP_001271308 NM_017828 NP_060298 NR_104312 NR_104313
|
| Function |
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B. {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:15799966}.
|
![Western Blot: COMMD4 Overexpression Lysate (Adult Normal) [NBP2-06911] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for COMMD4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8337_COMMD4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06911-img0001.jpg)